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October 15, 2008 (Vol. 28, No. 18)

Cashing in Your Chips to Advance Discovery

Chromatin Technology Uncovers Previously Unknown Regulatory Networks in Living Cells

  • ChIP-on-chip technology unites chromatin immunoprecipitation with microarray platforms in order to reveal protein/DNA interactions. By allowing the identification of protein-binding sites on DNA on a global genomic basis, it offers a new path to pharmaceutical discovery. ChIP-on-chip pairs chromatin immunoprecipitation (ChIP) with glass slide microarrays (chip) to analyze ...

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