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June 15, 2012 (Vol. 32, No. 12)

Capitalizing on miRNA Research

  • Aberrant expression of microRNA (miRNA) in human cancers is a common phenomenon. miRNAs regulate many tumor suppressor genes and oncogenes, therefore acting as oncogenes or tumor suppressor genes themselves to directly regulate cancer cell survival and proliferation. In tumor cells, inhibiting miRNAs that are overexpressed, and restoring intracellular ...

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