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May 01, 2009 (Vol. 29, No. 9)

ADMET Increasingly Integral to Discovery

Evolving Technology and Regulations Rapidly Advance a Formerly Extraneous Tool

  • Preclinical in vitro testing for ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties has come a long way in the decade since it became an important consideration in the discovery process. But it still has a long way to go. “Before the late 1980s to early 1990s, ADME ...

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