Corneal Injury Treatment Might Arise from Study That IDs Gene and Protein That Could Be Therapeutic Targets

Researchers at the Washington University School of Medicine in St. Louis analyzed genes expressed by the cornea in several mouse models—not only of dry eye disease, but also of diabetes and other conditions. They found that in mice with dry eye disease, the cornea activated expression of the gene SPARC. They also found that higher levels of SPARC protein were associated with better healing.