Candidate: COVID-19 XWG-03

Type: Recombinant protein-based vaccine combining Innovax’s XWG-03 vaccine technology and GSK’s pandemic adjuvant system, and based on multiple truncated S (spike) proteins.

Status: GSK disclosed in April it will make its pandemic adjuvant system available to Innovax to support preclinical evaluation of Innovax’s vaccine candidate against COVID-19, being developed with Xiamen University. Innovax plans to assess the S proteins to establish a lead candidate based on immunogenicity data. GSK and Innovax expanded a collaboration launched last year to develop a vaccine against human papillomavirus.

COVID-19: 200 Candidates and Counting

To navigate through the >200 potential therapeutic and vaccine options for COVID-19, GEN has grouped the candidates into four broad categories based on their developmental and (where applicable) clinical progress:

FRONT RUNNER – the most promising therapeutics/vaccines based on clinical progress, favorable data or both.

DEFINITELY MAYBE – earlier phases with promising partners, or more advanced candidates in development that have generated uneven data.

KEEPING AN EYE ON… – interesting technology, attracting notable partners, or both, but preliminary data.

TOO SOON TO TELL – longshots pending additional experimental and/or clinical data.

GEN has also tagged the most common treatment types:


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