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Biomarkers

Human Genes 10% More Numerous, If You Count smORFs

Biomarkers

Measuring Cancer’s Response to Treatment with a Liquid Biopsy Kit

At Left. A multiplexed pharmacodynamics assay was developed recently to assess immune checkpoint inhibitor–targeted CD8 activation and tumor colocalization in formalin-fixed paraffin-embedded tissues. The assay, which used oligo-conjugated antibodies supplied by Ultivue, achieved multiplex staining of CD8 (red), CD3z-pY142 (yellow), β-catenin (cyan), and Zap70-pY493 (not shown) on bead-activated CD3 cells from tissue spiked with interferon-γ-induced ACHN tumor cell lines. Staining of β-catenin allowed tumor cells to be differentiated from immune cells. Arrows point to CD8 cells that are CD3z-pY142+, indicating T-cell receptor activation.
Biomarkers

Biomarker Specialists Team Up, Run Up the Companion Diagnostics Score

Rectal cancer cell
Biomarkers

Synthetic Biomaterial Scaffold Could Serve as Early Cancer Diagnostic

Turning a dangerous toxin into a biosensor screenshot
Biomarkers

Aerolysin, a Toxin, Shows Promise as a Powerful Biosensor

Methyltransferase and DNA
Biomarkers

Methyl Group-Based Cancer Test Shows High Sensitivity and Specificity

ExRNAs in biofluid
Biomarkers

Prostate Cancer Screens Might Turn to Biomarkers in Semen

Biomarkers

Breathalyzer Sniffs Out Potential Cancer Immunotherapy Responders

MicroRNA molecule
Biomarkers

Cancer Biomarker Recognized in Methylated MicroRNA

Biomarkers

A Liquid Biopsy for Infectious Diseases?

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