Recent Advances and the Future of Antibody Engineering

VIEW NOW Broadcast Date: June 11, 2019 Time: 8:00 am PT, 11:00 am ET, 17:00 CET The therapeutic antibody market has reached a fever pitch of enthusiasm,...

Resistance to Antibiotic of Last Resort Found in Salmonella

The discovery of mcr-9, a gene that confers resistance to colistin, adds to the growing list of plasmid-mediated colistin resistance genes that were first described in E. coli in 2015. Because colistin is one of the world's few last-resort antibiotics, mcr-9 should be immediately considered when monitoring plasmid-mediated colistin resistance.

Measuring Multivalent Interactions: Uncovering the Secrets of Virus Binding Strategies

VIEW NOW Broadcast Date: June 13, 2019 Time: 8:00 am PT, 11:00 am ET, 17:00 CET Influenza A virus (IAV) utilizes a multivalent binding strategy to the...

Association Rate Constant: The Unsung Hero of Drug Discovery Kinetics

VIEW NOW Broadcast Date: May 21, 2019 Time: 8:00 am PT, 11:00 am ET, 17:00 CET While the importance of ligand-receptor binding kinetics on drug action is...

Keytruda Benefits Reported at AACR for Advanced Small Cell Lung Cancer

The anti-PD-1 monoclonal antibody immunotherapy pembrolizumab (Keytruda) is FDA approved to treat multiple types of cancer including melanoma, classical Hodgkin lymphoma, advanced cervical cancer,...

Omega-3 Deficiency Underlies Peripheral Artery Disease

A new study from a team of investigators at the University of California, San Francisco (UCSF) has just published evidence showing that individuals diagnosed...

Potential Leukemia Drug Target Found in Epigenetic Protein

Acute myeloid leukemia (AML) is an aggressive cancer that led to over 10,000 deaths in the United States last year. While AML is the...

Gut Microbiome Helps Warm the Cockles of Your Core

During cold exposure, it is well established that animals sustain their body temperature by activating heat production from a specialized tissue known as brown adipose tissue and promoting "browning" of white adipose tissue. Now, investigators have revealed the important role of gut microbiota in thermoregulation and adipose breakdown.

Cell-Free Protein Synthesis Made Flexible and Accessible

Researchers say they greatly simplified the method for cell-free protein synthesis

Metabolic Enzyme Pathway Identified as Potential Colon Cancer Target

University of Massachusetts (UMass) Amherst food scientists have identified a set of metabolic enzymes that are upregulated in colon cancer-bearing mice and in human...

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