Obesity Fuels Tumors but Boosts Checkpoint Inhibitor Therapy

UC Davis Health studies show that obesity induces immune suppression and promotes tumor growth through mechanisms that can be reversed using checkpoint inhibitor immunotherapy. The paradoxical findings give cancer doctors important new information when choosing drugs and other treatments for cancer patients.

Immunotherapy for Treating Malaria?

Checkpoint blockade may be key for immunity to malaria

University/Industry Research Team to Explore Melanoma Immunotherapies

Genocea will carry out a joint research project with Dana-Farber and Harvard Medical School to characterize antitumor T-cell responses in melanoma patients.

ImmunoCellular Brings Second Manufacturing Site for Cancer Vaccine Online

Firm completed tech transfer process from UPenn to Progenitor Cell Therapy’s California site.

Novartis to Buy 85% of Chinese Vaccines Company for $125M

In addition to Zhejiang Tianyuan BioPharmaceuticals, Novartis invests in a new Institute for BioMedical Research in Shanghai and a center for APIs in Changshu.

OriGene Raises $16M to Create the Largest Collection of mAbs

Firm is building the TrueMAB collection to cover the entire human genome and will consist of antibodies that are significantly different from many on the market.

Synta and Madrigal to Merge, Focused on CV Diseases and NASH

Combined company's lead compound will be Madrigal’s Phase II-ready MGL-3196, indicated for HeFH and HoFH as well as NASH

Teva-Compugen Alliance Yields Biomarkers for Detection of Drug-Induced Kidney Toxicity

Teva will use the panel in its R&D activities, and Compugen plans to commercialize it later this year. Teva Pharmaceutical Industries exercised its option to...

Study Shows How Bacteria Become Antibiotic Resistant

Scientists from Denmark and Switzerland say they have shown that bacteria produce a stress molecule, divide more slowly, and thus save energy when they...

NIPTE Receives $35M from FDA to Reform Drug Manufacturing Standards

Institute expects improved standards to reduce costs and need to outsource production work.

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