Sartorius Stedim Biotech Becomes Major Owner of AllPure Technologies

Sartorius Stedim Biotech signed a deal to acquire the majority stake in AllPure Technologies.
CRISPR-Cas9 protein

Novel CRISPR-Cas9 Variants Generated by Diverse Means

CRISPR-Cas9 can perform its usual tasks more ably, or assume new ones, if it is subjected to protein engineering. The available protein engineering approaches include rational design, directed evolution, and domain fusion.
The left-side group of mice is a control—with neither the gene-editing RNA nor the BOC switch. The next group has BOC but no RNA

Biological Switch May Offer Better Control of Gene Editing

Team invents biological switch that turns protein expression on at will

BIA Separations Introduces PrimaS Multi-Mode Ligand Bioprocess Technology

New platform designed to initially focus on high-resolution industrial scale processing of therapeutic mRNA.

Novartis Cuts 300 Jobs, Names New CFO

Reporting its first-quarter financial results this week, Novartis announced a restructuring of its Lincoln, Nebraska manufacturing plant and its naming of a new CFO.
Scientist in a clean room

The Move toward Biopharma 4.0

Insilico Biotechnology describes its Digital Twins technology, which combines mechanistic modeling and AI to optimize bioprocesses and realize the “factory of the future.”

Sanofi Inks Bispecific Antibody Deal with Biomunex

Sanofi will use Biomunex Pharmaceuticals’ proprietary BiXAb® platform for generating and optimizing bi- and multi-specific antibodies to develop new treatments in immuno-oncology and other therapeutic areas. The companies have signed a licensing agreement whose value...

CSL Negotiates Option to Pevion’s Candida Vaccine for Australia and New Zealand

Virosome-based vaccine is in early clinical development for treating chronic recurrent thrush.

ArmaGen Chooses PacificGMP to Manufacture Fusion Protein for Phase I Trial in Stroke and...

A perfusion process will produce AGT-190, which comprises a neuroprotectant, neurotrophin, fused to a protein that can carry it across the blood-brain barrier.

GTC Bolsters FOB Development Plans through Deal with AgResearch

AgResearch will create transgenic founder animals for production. GTC Biotherapeutics entered into a collaboration with AgResearch to develop transgenic founder animals for the production of two follow-on biologic (FOB) mAbs. GTC points out that securing...

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