mRNA Technology - Messenger RNA - Two Strands of mRNA on Abstract Technology Background

mRNA Vaccine Stabilization through Modulating LNP Composition and Utilizing Drying Technologies

In this GEN webinar, our distinguished guest, sponsored by Precision NanoSystems, Dr. Roland Böttger, will discuss aspects of mRNA stability, focusing on LNP formulation. Moreover, Dr. Böttger will show that the LNP composition is key to enabling advanced stabilization technologies such as dry mRNA presentation for storage at ambient temperatures.

DMPK Optimization of Proteolysis-Targeting Chimeras

In this GEN webinar, sponsored by WuXi AppTec, our distinguished guest, Dr. Liping Ma, will focus on tackling the DMPK challenges of developing proteolysis-targeting chimeras by providing a research strategy for conducting in vitro ADME and in vivo PK studies, with the goal of helping drug developers quickly advance their projects.
mRNA - Vaccine against Novel Coronavirus 2019-nCoV

Speed and Simplicity for mRNA Vaccines and Therapeutics CQA Testing

In this GEN webinar, our distinguished speaker Dr. Kathy Rowlen, CEO and co-founder of InDevR, will detail the performance characteristics of a VaxArray Assay for multivalent influenza mRNA formulations that include constructs for both hemagglutinin and neuraminidase.
High-speed particle flow effect

Ultrahigh Sensitivity Mass Spectrometry in Immunoproteomics and Bioinformatics

In TODAY's GEN webinar, sponsored by Bruker, our distinguished presenters, Dr. Stefan Tenzer and Dr. Jonathan Krieger will explore deep immunopeptide profiling from small sample sizes and the latest bioinformatic capabilities using real-time searching on PaSER for ultrahigh sensitivity proteomics.
Replication and transcription of HIV.

Improving Lentiviral Vector Yields and Scalability for Advanced Therapies

In TODAY's GEN webinar, sponsored by WuXi, our expert panelists will discuss how they aim to develop technologies to improve Lentiviral vector yields and scalability. Specifically, we will hear about the challenges involved with the large-scale manufacture of Lentiviral vectors and how OXGENE’s LentiVEX™ plasmids are designed for high vector yields and can be used within transient manufacturing platforms.
CAR T-Cell Immunotherapy

Transcription Factors Driving CAR T Cell Dysfunction

In this GEN webinar, sponsored by 10x Genomics, we will learn how our guest presenter, Dr. Charly Ryan Good from UPenn, studies the dysfunction of mesothelin-redirected CAR T cells in pancreatic cancer.
Cytokine production in activated macrophages

Ultra-Sensitive IL-11 Target Engagement Assay Development

In this GEN webinar, sponsored by Quanterix, we will learn some insights into IL-11’s role in fibrotic diseases of the lung, liver, and kidney.
Virus variant, coronavirus, spike protein. Omicron. Covid-19 seen under the microscope

SARS-CoV-2 Cell Surface Nucleocapsid Protein Modulates Innate and Adaptive Host Immunity

Cell surface N may play an important role in host adaptive immunity to SARS-CoV-2 and in manipulating innate immunity at the early stages of infection. In TODAY's GEN webinar, sponsored by Sartorius, our distinguished speaker Dr. Alberto Lopez-Munoz from the NIH will show how he finds that N is expressed on the cell surface of live cells in high copy numbers and that it binds to infected and non-infected neighboring cells by electrostatically associating with glycosaminoglycans.
3d render illustration of Single strand ribonucleic acid. RNA research and therapy

Challenges and Considerations for mRNA Therapeutic Development

This is the second webinar in a series of four, cohosted by GEN and The CRISPR Journal, that is diving deep into the burgeoning world of mRNA research and therapeutics. Our distinguished guest for this event, Dr. Edward Miracco, will take us through his extensive experience with mRNA chemistry, sequence design, and commercial-scale production.
Bioinformatics and Biostatistics Concept

Modernizing Your In Vivo R&D Programs

In this GEN webinar, sponsored by Benchling, we will share some of the frequent challenges observed across the industry, followed by real-world examples of companies modernizing their in vivo programs and a demonstration of a cloud-based informatics solution called Benchling Studies.