eBooks

In this eBook, sponsored by Isoplexis, we will cover recent cutting-edge research in cellular therapy, as well as several cases in which functional proteomics technology was used to optimize cell therapies at every stage of the development pipeline, filling critical gaps in cell therapy product quality assessment and predictive biomarker discovery.

This roundtable, sponsored by Isoplexis, highlights how scientists are mining single-cell proteomic data to identify and understand dynamic proteomes in high-functioning immune cells and their immune impact. Our expert panel discusses the development of new cell and immune therapies that target tumors, based on the insights gleaned from proteomic profiles of multifunctional immune cells.

Creative endeavors—including drug discovery—bring to mind that old saying, “Think outside the box.” That’s a good saying, but when the box is the human cell, it is necessary to think inside the box, too. Also, it helps to think about what’s within. In this eBook, sponsored by Sartorius, we consider all these perspectives.

This eBook, sponsored by Cytiva, dives into some of the current challenges that biomanufacturers face when analyzing their production streams for impurities and what they are doing to improve detection methodologies for HCPs.

In this eBook, sponsored by Thermo Fisher Scientific, we examine the rising role of genetics in medical diagnostics, including polymerase chain reaction (PCR), genomic sequencing, and gene-based microbiome disease association. This collection of articles looks at the dramatic increase in prevalence of PCR testing since the onset of the COVID-19 pandemic, and explores the possibilities of still deeper, wider spread clinical applications for PCR in the not-so-distant future.

2020 was devastating. It was also a year of firsts. Fueled by decades of research and widespread global cooperation, the first mRNA-based vaccines against SARS-CoV-2 were produced, tested, and injected mere months after COVID-19 hit. With mRNA technology proven, the floodgates are now open to a deluge of possibilities. We’ve got some of the brightest and most industrious on the case to solve the challenges unique to mRNA. Read this collection of articles to join the mRNA evolution and bring more ‘firsts’ to patients.

This content collection, sponsored by Sartorius, will highlight the key challenges and points to consider during the CLD workflow, the impact early data-driven decision-making can have on later stages of development, and how to accelerate process optimization by incorporating innovative analytical techniques.

Digitalization holds great promise for increasing the efficiency, quality, and reproducibility of upstream bioprocessing. With this eBook, sponsored by Eppendorf, we would like to explore the growing world of bioprocess digitalization. How can the bioprocess industry benefit from digitalization? What are concrete examples of process automation? And how can artificial intelligence transform bioprocessing?

This eBook examines the suite of technologies leading the fight in the war on SARS-CoV-2, highlighting the importance of initial viral detection and ongoing biosurveillance to limit its spread and damage – to both human life and our way of life. The six articles – written by leaders in their fields and researchers on the front line – examine these ground-breaking tools, methods and workflows in detail.

In this new eBook created through a collaboration between experts at Sartorius and the University of Nantes, we explore various aspects of upstream rAAV production. The authors discuss the challenges that rAAV experts face and propose some of the best practice solutions they have employed to overcome them. Through a series of opinion-led and case study articles, you’ll learn how combining new technology such as high throughput mini bioreactors and Design of Experiments (DOE) software can help rapidly optimize rAAV production.