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A malaria parasite (yellow) invading liver cells (pink/red). Researchers showed that carbohydrates on the surface of the parasite play a critical role in malaria's ability to infect mosquito and human hosts. [WEHI.TV/Walter and Eliza Hall Institute of Medical Research]
Post-Translational Modifications

For Malaria Vaccines to Improve, They’ll Need to Get Sweeter

Post-Translational Modifications

Autism Gene Alters Synapse Development

A study of acquired heart failure implicates a protein clumping mechanism triggered by a mono-phosphorylated form of desmin. The study also shows that toxic clumping can be detected by positron emission tomography (PET). (Top) A PET scan detects clumping proteins in rat hearts. (Right) The enlarged heart is one with heart failure. (Bottom) Other PET scans showing blood flow in the rat hearts show that the protein clumps aren't due to circulation problems. [Courtesy of Circulation Research
Post-Translational Modifications

Alzheimer’s-Like Clumping Proteins Found in Diseased Hearts

Post-Translational Modifications

How Proteins Betray Their Age, Succumb to Forced Retirement

Post-Translational Modifications

Proteome Sciences and Buck Institute Ally on MS-Based Anti-Estrogen Therapy Resistance...

Glycosylation enzyme molecule
Post-Translational Modifications

Successfully Addressing the Challenges of Glycosylation

Synthetic biomaterials can draw on the power of post-translational modification to accomplish temperature-triggered self-assembly
Post-Translational Modifications

Self-Assembling Lipid–Polypeptide Biomaterials Follow Heat Cues

NISTmAb monoclonal antibody
Post-Translational Modifications

Getting at Glycosylation

tobacco field
Post-Translational Modifications

Building Therapeutic Proteins through Plant Glycosylation: A Sweet Solution

Stroke patients may be protected against ischemic brain damage if the protein-modifying and -regulating secrets of hibernating animals are used to identify new drug candidates. For example
Post-Translational Modifications

Stroke Relief Ideas from Ground Squirrels Aren’t Nuts

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