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Post-Translational Modifications

Glycosylation

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Post-Translational Modifications

Optimize Protein Glycosylation—and—Yield by In Vitro Glycoengineering

A study of acquired heart failure implicates a protein clumping mechanism triggered by a mono-phosphorylated form of desmin. The study also shows that toxic clumping can be detected by positron emission tomography (PET). (Top) A PET scan detects clumping proteins in rat hearts. (Right) The enlarged heart is one with heart failure. (Bottom) Other PET scans showing blood flow in the rat hearts show that the protein clumps aren't due to circulation problems. [Courtesy of Circulation Research

Post-Translational Modifications

Alzheimer’s-Like Clumping Proteins Found in Diseased Hearts

Post-Translational Modifications

To Shut Down Cancer Cells, Try Giving Them Alzheimer’s

Post-Translational Modifications

Streamlining Glycan Analysis: From Sample Preparation to Data Analysis

Post-Translational Modifications

Addressing the Challenges in Maintaining and Analyzing Biotherapeutic Glycosylation

Metabolocentric approaches to treating metastatic breast cancer could be advanced by targeting a signaling mechanism that is inhibited by obesity-associated cytokines such as leptin. In this image

Post-Translational Modifications

Obesity Tilts Breast Cancer Cells toward Metastasis by Suppressing Metabolic Enzyme

Stroke patients may be protected against ischemic brain damage if the protein-modifying and -regulating secrets of hibernating animals are used to identify new drug candidates. For example

Post-Translational Modifications

Stroke Relief Ideas from Ground Squirrels Aren’t Nuts

Post-Translational Modifications

Glycobiology Advance May Lead to Novel Cancer Therapies

Post-Translational Modifications

Diabetes, Alzheimer’s Share Molecular Pathways, Part of Same Vicious Cycle

Synthetic biomaterials can draw on the power of post-translational modification to accomplish temperature-triggered self-assembly

Post-Translational Modifications

Self-Assembling Lipid–Polypeptide Biomaterials Follow Heat Cues

Post-Translational Modifications

Targeting Glycans Puts Icing on T-Cell Therapy

Post-Translational Modifications

Cell Division the Outcome of an Adversarial Process

Post-Translational Modifications

Making Sense of Glycosylation Using Novel Hydrophilic Interaction Liquid Chromatography Techniques

Post-Translational Modifications

Autism Gene Alters Synapse Development

Post-Translational Modifications

Team Develops More Effective Therapeutic Antibodies

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