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Post-Translational Modifications

Potential New Drug Targets ID’ed for Deadly Viruses

Post-Translational Modifications

Genetically Encoded Frankenbody Lights Up Live Cell Imaging

Post-Translational Modifications

In Pancreatitis and Pancreatic Cancer, a Supposed Bystander May Be a...

Post-Translational Modifications

Natural Anti-Parkinson’s Mechanism Discovered That Targets Fibrils, Prevents Lewy Bodies

A study of acquired heart failure implicates a protein clumping mechanism triggered by a mono-phosphorylated form of desmin. The study also shows that toxic clumping can be detected by positron emission tomography (PET). (Top) A PET scan detects clumping proteins in rat hearts. (Right) The enlarged heart is one with heart failure. (Bottom) Other PET scans showing blood flow in the rat hearts show that the protein clumps aren't due to circulation problems. [Courtesy of Circulation Research
Post-Translational Modifications

Alzheimer’s-Like Clumping Proteins Found in Diseased Hearts

Synthetic biomaterials can draw on the power of post-translational modification to accomplish temperature-triggered self-assembly
Post-Translational Modifications

Self-Assembling Lipid–Polypeptide Biomaterials Follow Heat Cues

Post-Translational Modifications

Glycobiology Advance May Lead to Novel Cancer Therapies

Stroke patients may be protected against ischemic brain damage if the protein-modifying and -regulating secrets of hibernating animals are used to identify new drug candidates. For example
Post-Translational Modifications

Stroke Relief Ideas from Ground Squirrels Aren’t Nuts

Metabolocentric approaches to treating metastatic breast cancer could be advanced by targeting a signaling mechanism that is inhibited by obesity-associated cytokines such as leptin. In this image
Post-Translational Modifications

Obesity Tilts Breast Cancer Cells toward Metastasis by Suppressing Metabolic Enzyme

Source: Dna621/Wikimedia
Post-Translational Modifications

CRISPR Identifies Rare Type of Glycosylation Critical for Cancer

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