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![Flex Pharma cites unspecified “oral tolerability concerns” in halting Phase II trials of FLX-787 in amyotrophic lateral sclerosis (ALS) and Charcot-Marie-Tooth (CMT). [© whitehoune / Fotolia]](https://www.genengnews.com/wp-content/uploads/2018/08/170123090806_1_900x6009916143062-324x160.jpg "Flex Pharma Axes 60% of Workforce, Explores Sale after Halting Phase II Trials in ALS, CMT")
![The hnRNP A1B is expressed in the central nervous system and forms cytoplasmic aggregates in ALS patient neurons. [CRCHUM]](https://www.genengnews.com/wp-content/uploads/2018/08/Mar19_2018_CRCHUM_hnRNPA1B2262381965-324x160.jpg "Hope for ALS Patients Comes from New Understanding of RNA Metabolism Misregulation")
