May 2021 Vol. 41 No. 5

Plant-based production will play a key role in the fight against COVID-19 and its variants as developers embrace low-cost alternatives to traditional manufacturing methods.

To perform the operation at the optimal time, the fermentation process is monitored at discrete intervals. The time since the last bioreactor setup or bleed-feed, the cell culture growth rate, and the number of bleed-feed operations performed are each recorded. At each step, the decision is made to continue or to bleed-feed. Bleed-feed implementation takes six to nine months. Ranges were established for critical process parameters.

The pharmaceutical industry adapted remote and hybrid audits during the pandemic to audit their supply chain without compromising on quality. This includes auditing suppliers of products ranging from the bags needed for single-use manufacturing to the barcoded product labels. New approaches pharma adopted included remote auditing by video link using software ranging from dedicated secure connections to a simple Facetime call on a mobile phone.

Plant-based production will play a key role in the fight against COVID-19 and its variants as developers embrace low-cost alternatives to traditional manufacturing methods.

To perform the operation at the optimal time, the fermentation process is monitored at discrete intervals. The time since the last bioreactor setup or bleed-feed, the cell culture growth rate, and the number of bleed-feed operations performed are each recorded. At each step, the decision is made to continue or to bleed-feed. Bleed-feed implementation takes six to nine months. Ranges were established for critical process parameters.

The pharmaceutical industry adapted remote and hybrid audits during the pandemic to audit their supply chain without compromising on quality. This includes auditing suppliers of products ranging from the bags needed for single-use manufacturing to the barcoded product labels. New approaches pharma adopted included remote auditing by video link using software ranging from dedicated secure connections to a simple Facetime call on a mobile phone.