October 15, 2006 (Vol. 26, No. 18)


Strong Points: Easy access to analyses
Weak Points: A bit narrowly focused

Alternative splicing is an important topic, what with the discovery of considerably fewer genes in the human genome than expected. What we lack in raw numbers, we make up for by mixing and matching sequences, and that is where ProSplicer comes in. Providing an alternative splicing database, based on protein, mRNA, and EST sequences, ProSplicer offers several useful search tools to the user. They include searches for gene names and gene sequences using several naming formats (gene searches) and options for searching protein or DNA sequences of genes. An excellent online paper about ProSplicer informs users of the technical considerations built into the site. This is an essential site for anyone interested in gene expression in eukaryotes.

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