May 15, 2018 (Vol. 38, No. 10)
URL:
http://pharmit.csb.pitt.edu
Rating:
Strong Points: Vast collection of compounds and conformations, good graphics display
Weak Points: None
Summary:
Phamacological screening of compound libraries in the laboratory is costly and time consuming. So, the creators of this website at the University of Pittsburgh invite researcher to “pharm” out the work to the Pharmit virtual-screening platform. The Pharmit visualization environment runs within a web browser and grants users access to six built-in libraries containing close to 100 million compounds in over 1 billion total conformations. Users can search for proteins via their Protein Database (PDB) IDs; however, the site also provides some samples for users to explore when they’re just getting started on the website. The graphics display nicely within the browser, with only slight lag when viewing the molecules at high zoom. Within the visualization browser, users can search through specific ligand libraries. Search results appear on the right side of the page, and each ligand can be displayed in its predicted binding location by selecting on the corresponding search result.
