May 15, 2014 (Vol. 34, No. 10)


Strong Points: Large number of specimens, videos, and image stacks
Weak Points: None


There is no shortage of “eye candy” in biology, with the many high-resolution imaging and image reconstruction techniques. At, curious onlookers can peruse image stacks and movies of 3D reconstructions of mouse embryos collected by high-resolution episcopic microscopy (HREM). The website highlights an ongoing project to generate comprehensive 3D reconstructions of mutant and wild-type embryos to address a gap in the anatomical literature and ultimately facilitate phenotyping. At present the site contains an assortment of wild-type specimens collected at seven different time points, from E9.5 to E15.5. Additionally, the website also contains datasets for close to one hundred mutant mouse lines. Site visitors can browse the data in either image stack or video form. In stack form, the images load one-by-one and there is no continuity between them; the videos, on the other hand, show either the continuous projection through a given image stack or the 3D reconstruction of the embryo.

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