May 15, 2014 (Vol. 34, No. 10)
Strong Points: Downloadable data, unpublished results
Weak Points: None
The Center for Cancer Systems Biology (CCSB) at the Dana Farber Cancer Institute has invested (and continues to invest) a great deal of time and resources in mapping binary protein-protein interactions, as evidenced by the CCSB Interactome Database website. On this website, one will find information about efforts to map the human interactome, the flagship project of CCSB, as well as updates on various other mapping projects of the Center, such as those to map virus-human protein interactions and binary protein interactions in either A. thaliana or C. elegans. The website includes descriptions of each project (including progress reports), links to resulting publications, and access to unpublished data. For each individual interactome database (such as the virus-human database), one can search for specific interactions and download the complete datasets.