January 1, 2010 (Vol. 30, No. 1)
Strong Points: Variety of search parameters, easy to navigate interface
Weak Points: Nothing significant
Just how many ways can you search for enzymes, you ask? Well that is a question to be posed to BRENDA, the “comprehensive enzyme information system” designed by a group at the Technical University of Braunschweig. BRENDA is quite impressive, with over 50 (that’s right, 50!) different search parameters for enzymes. To get an idea, one can search by metabolic pathway, enzyme turnover number, oxidation stability, post-translational modifications, molecular weight, etc. The list goes on and on. The page design is nothing fancy, but beneath the simple interface lies a great deal of information waiting to be unearthed. One need only click to display “all enzymes in BRENDA” to gain an appreciation for the scope of the information. So what are you waiting for? Go catch up on some catalysis!