Rating: Very Good
Strong Points: Displays full protein structures, some information given about each enzyme
Weak Points: None
Platform: iPad/iPhone/Android
Cost: Free
The CRISPR-Cas9 system, which allows for precise gene editing, has revolutionized the way that scientists do biology. However, Cas9 isn’t the only enzyme associated with CRISPR sequences. CRISPR-3D allows you to take a closer look at all of these associated enzymes right from your phone using augmented reality. CRISPR-3D includes a short tutorial for new users to learn how to use the app, and then lets users explore Cas1 through Cas13 in three dimensions. Each enzyme includes a short description about its known function, and users can take screenshots of each model. Additionally, the app divides each model into layers according to function. For example, users can choose to look specifically at the protein itself, the ATP binding spot, or where the single-stranded RNA associates with the enzyme. Although Cas9 gets all of the credit when it comes to CRISPR technology, CRISPR-3D is a great app for those curious about the structures of the variety of other Cas proteins.
