Digital Pharma
Source: Leo Woflert/Getty Images

By Akhilesh Ayer and Mark Halford

Pharma companies have long been playing a critical role in our lives while staying mostly in the background. However, COVID-19 has pushed the pharma industry firmly to the foreground. Governments and societies are pinning their hopes on the industry’s ability to help prevent the next epidemic while continuing to find cures for known health conditions and diseases.

Navigating a complex and fast-changing landscape

Akhilesh Ayer
Akhilesh Ayer, Head of Research and Analytics, WNS

In the wake of the pandemic, pharma companies face a growing number of challenges, especially in relation to research and development (R&D). Costs have spiraled over the last decade. According to Statista, the pharma industry’s R&D spending in 2020 totaled about $200 billion globally. The journey from preclinical research to marketing can take anywhere between 12 to 18 years, pushing any kind of return on investment into the distant future and increasing the risk to company finances, particularly with respect to liquidity. And now, because of the precedent set by the pharma industry’s COVID-19 response, there is the expectation that essential vaccines will be developed quickly.

The growth of generics is eating away at market share, and regulations have become more complex. Pharma companies that fall foul of the rules can expect not just fines, but greater reputational damage than ever.

Mark Halford
Mark Halford, Senior VP, Client Services, Life Sciences and Healthcare, WNS

Developing drugs to combat new and sometimes little understood conditions is particularly time consuming and costly. And developing treatments that offer really significant improvements over existing products is also challenging. Meanwhile, the U.S. Food and Drug Administration (FDA) has signaled its desire to bring more competition to the pharma market in an attempt to reduce the cost of medicines.

To remain competitive, drug companies need to invest in their R&D systems to speed up the discovery process. As industries across the board move toward a digital-only world, pharma companies must account for the different technologies that are transforming the R&D process. Digital adoption is the future of the pharma industry, and it is essential thatpharma companies understand which technologies can deliver faster, more effective R&D.

Tapping into the immense potential of AI

Artificial intelligence (AI) offers forward-thinking pharma companies the opportunity to revolutionize their drug discovery and development processes. Hong Kong–based Insilico Medicine, for instance, has used AI and deep learning to design, synthesize, and validate a novel drug candidate in 46 days—15 times faster than what was previously thought possible.

As the Insilico Medicine case study demonstrates, it is already clear that AI, guided by humans, has the potential to manage the vast number of compound permutations needed for drug design. This fast-evolving technology enables the aggregation, harmonization, and analysis of multiple data sources needed for discovery, design, and clinical trials, thereby shortening the drug development process.

AI can increase novel drug discovery, minimize potential drug interactions, enhance the understanding of disease mechanisms, speed drug design, identify biomarkers, run preclinical experiments, design clinical trials, and provide deep insights more efficiently. It can be leveraged to predict the medicines that will ultimately work and the ones that will not, thus helping to reduce the investment in candidates unlikely to make it to market.

By becoming fully digital, pharma companies can gain real-time competitor insights and keep abreast of change in drug regulations across regions. With the use of AI and data analytics, they can streamline knowledge collation via available public and commercial data sources. This instantly provides R&D teams with insights needed on their competition as well as intelligence on local regulations, emerging conditions in a particular regime, and the release of new drugs into the market.

AI and data analytics can process vast amounts of data, some of which is unstructured, in a fraction of the time taken by human beings. AI can “learn” what trends and developments to look out for in the data and alert human beings only to what is relevant.

Advancing CI with AI and cloud technology

Cloud-based platforms allow pharma companies to become more agile, as they provide an immediate, interactive, and customizable way of storing competitor intelligence (CI) data. With a cloud-based platform, users can access insights across devices such as tablets, smartphones, or desktops—through highly secure and seamless authentication. This is particularly important for sales representatives or attendees of conferences and meetings, as vital information can be shared quickly among all relevant parties within the organization.

Pharma groups can integrate their cloud solutions across company systems in a way that combines both business intelligence tools and commercial data. These platforms are customizable so that they can display in-house and external news, competitor profiles, and sales and pricing information via easily accessible dashboards and layouts. Combining valuable data analytics insights, AI, and cloud-based platforms streamlines the retrieval of market insights for R&D teams.

Insights from CI have always enabled pharma companies to identify their core strengths in relation to their competitors. As well as transforming drug development, AI can enhance CI to cope with rapidly evolving markets and greater disruption. Detailed, accurate, and timely CI can help companies target unmet needs to transform not just their offerings, but entire business models. The analysis of the competitive environment can also help companies focus their R&D efforts. This helps benchmark performance, identify strengths, and highlight priority areas. Superimposing results from business intelligence and CI helps pharma companies identify new avenues to differentiate their brands and fulfill market needs as they emerge.

Cloud computing can be used to complement AI-powered tools as they harvest data from millions of website pages to draw out valuable insights by tracking a competitor’s entire digital footprint, both on and off that competitor’s site. Together, technologies can measure everything from changes in the price of competitors’ products to new appointments. Natural language processing can analyze the sentiment that competitors’ brands are experiencing on social media, and it can read customer reviews on a wide variety of platforms and convert it into usable data and actionable information.

Cloud computing enables companies to effortlessly increase or reduce their storage requirements for CI data. The insights that they develop can also be easily shared across all departments, from R&D to finance, on a variety of devices using intuitive interfaces such as dashboards.

Factoring in the obvious challenges

As pharma companies rush to adopt these new technologies, they are bound to run into obstacles. For example, current patent laws usually prevent AI from being acknowledged as an “inventor.” Hence, AI inventions are not protected as well as traditional innovations. Also, data stores, including stores of genetic code, are becoming larger and more varied. Consequently, security risks are evolving, necessitating new governance measures.

AI will be limited by processing speeds, requiring pharma companies to adopt new technologies in their endeavor of maximizing AI impact. As competitors possibly compress years of product research, development, and launch efforts into mere months, companies will need to ensure that their CI can keep pace.

Even the largest pharma companies need to look for trusted technology partners to help them benefit fully from AI. As they focus on their core competencies, they can work alongside these partners, with their specialist knowledge and capabilities, to draw up a road map for the adoption of AI. Their partner organization should be able to identify the right solutions and then scale them up rapidly in a controlled environment.

CI platforms, such as the PRECIZON platform from WNS, have built-in readiness for the rapid acceleration of R&D enabled by AI. The pace of the market will increasingly demand machine learning intelligence for real-time user recommendations and content classification. Delivered on the cloud, such technologies can be integrated into other core systems with personalized content available through all devices. As AI increases pipeline pace, such scalable enterprise tools are becoming vital. They can ensure that automated systems foster collaboration and deliver insights.

Ranking is a machine learning technique for recommendation systems such as intelligent CI. In what are known as “clustered approaches,” information about user behavior can be utilized to recommend items. These recommendations are generated with user-user or item-item similarity. Based on these similarity measures, the resulting suggestions are provided to the user. By predicting these user preferences, the portal delivers effortless user engagement.

The time for innovation is now

Interestingly, these innovative technologies feed off of each other. As the growth of AI and automation drives various facets of pharma operations to become digital-only, enterprises will increasingly find themselves storing data on cloud-based platforms. They need to start now by integrating these new technologies into their everyday workflows to stay relevant and ahead of the competition.

Innovation has always been at the heart of the pharma industry. However, the urgency for new drugs is greater than ever, even as risks and uncertainties continue to mount. Implemented correctly, AI and other technologies will enable agile, forward-thinking companies to manage these risks, exploit new opportunities, and deliver for their employees, shareholders, and patients around the world.

 

Akhilesh Ayer is the head of research and analytics at WNS, and Mark Halford is the company’s senior vice president of client services, life sciences and healthcare.

Previous articleTackling Life’s Toughest AI Challenge
Next articleThe Future of Biotech in an Artificially Intelligent World