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GEN Presents An Educational And Informative Webinar

Employing Metabolomics in Cell Culture and Bioprocessing: Gaining greater predictability, control and quality

  • Broadcast Date: Thursday, July 25, 2013
  • Time:

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Challenges in developing and producing biotherapeutics are numerous and dynamic, including various market drivers and industry responses. Finding effective measures to support a foundation of control, predictability, and quality have been a concern and have paved the way to seeking out and applying newer technologies such as metabolomics successfully to bioprocessing. This webinar will first navigate through the landscape and challenges in developing and producing biotherapeutics. The journey continues with a walk through of the rationale for why metabolomics is a key tool for addressing critical bioprocessing needs followed by specific case studies and examples of how a functional metabolomic approach has been applied.

 

There are many relevant applications for functional metabolomics in bioprocessing starting with process development that include being able to: boost titer or productivity, improve product quality, enhance viability, or optimize defined media. The technology has be employed in biomarker discovery applications for the following purposes: to identify predictors of lactate consumption, to assess product quality, to predict indicative biomarkers of bioreactor performance or identify ideal clones. Lastly, functional metabolomics has been applied to enrich DOE experiments and troubleshooting for: historical deviation, process transfer, scale-up issues, disposable concerns, and lot or performance changes.

 

For additional application-specific questions or information, inquire at info@metabolon.com or visit our website at www.metabolon.com. A complementary consultation is available anytime upon request.

A live Q&A session will follow the presentations, offering you a chance to pose questions to our expert panelists.

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Panelists

  • Kirk Beebe, Dr.,
  • Director of Application Science
  • Metabolon Inc.

Produced with support from