Advancing Genomics into Personalized Medicine

• Broadcast Date: Wednesday, December 14, 2011
• Time: 1:30 PM EST

REGISTRATION IS FREE

AVAILABLE ON DEMAND

High-throughput technology and the data it generates is evolving and advancing basic science into clinical science and personalized medicine. But while currently available methods exist to rapidly and efficiently produce DNA, epigenetic, and RNA whole-genome profiles from individual tissue samples and cell lines, data analysis and deconvolution remain challenging.

To address this issue, methods of knowledge-based functional analysis such as ontology enrichment, interactome, and causal networks have been developed.

These analyses rely on databases designed to accommodate complex aspects of mammalian functionality, for example, coordinated expression of multiple genes to effect a single function, RNA splice variants, or protein isoforms.

Webinar participants will discuss knowledge-based analytical methods, and how they can be used for functional analysis of OMICs datasets by cheminformatics and bioinformatics software tools such as network-generation algorithms, ontology enrichment, interactome calculations, and pathway modeling.

The application of these analytical methods to advances in understanding breast tumor heterogeneity and the potential development of a targeted therapy based on this knowledge will also be discussed.

In This Webinar You Will Learn

• How scientists are applying knowledge-based functional analyses for translation research.
• How these tools can enhance potential success in rational drug design.
• How these tools were used to analyze results of large-scale shRNA loss of function screening to identify potential breast cancer drug candidates.

Who Should Attend

• Genomics scientists
• Proteomics scientists
• Targeted drug development scientists
• Cancer biologists
• Bioinformatics scientists

Panelists Include

• Kornelia Polyak, M.D., Ph.D., Associate Professor of Medical Oncology, Dana-Farber Cancer Institute
• Craig P. Webb, Ph.D., Professor, Cancer Genomics and Computational Biology, Van Andel Research Institute
• Yuri Nikolsky, Ph.D., Vice President, Research & Development, Thomson Reuters

John Sterling, Editor in Chief, Genetic Engineering & Biotechnology News, will be the host of this webinar. A live Q&A session will follow the presentations, offering you a chance to pose questions to our expert panelists.

AVAILABLE ON DEMAND