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Advances in the Analysis of Glycans for the Characterization of Biopharmaceuticals

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  • Sponsored by Waters

Many protein-based biopharmaceuticals are glycosylated proteins. The glycans themselves directly affect the efficacy and safety of the biopharmaceutical. Measurements of the sites of glycan attachment, the glycans that are present, and the relative proportions of each alternative structure are required for both pharmaceutical and regulatory reasons. The number and similarity of possible structures of these molecules place tremendous demands on the analytical techniques. Recent advances in chromatographic approaches have led to better resolution, sensitivity, and speed for greater reliability in the qualitative and quantitative analysis of protein glycosylation....learn more


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INTERVIEW: WHY JUNK DNA IS NOT TRASH - Inteview with Kevin Verstrepen, Ph.D., Group Leader, Laboratory of Systems Biology, Flanders Institute for Biotechnology, and Associate Professor, Biological Engineering, Catholic University of Leuven ...MORE

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