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Dr. James Wilson is a professor in the department of pathology and laboratory medicine, and the director of the gene therapy program, at the University of Pennsylvania. He is also the editor of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc. During this interview with GEN, Dr. Wilson discusses his concept of a disruptive technology and explains why he believes gene therapy falls into this category.
In addition to this SKYPE interview, Dr. Wilson further elaborated on his view of gene therapy as a disruptive technology in a column in the January 2012 issue of Human Gene Therapy which you can access by clicking here.
DNA: Past to Present
In celebration of DNA Day on April 25, GEN presents this video timeline spanning 150 years of the history of DNA.
Exploring the PI3K/AKT/mTOR Pathway
Novartis Oncology is investigating the PI3K/AKT/mTOR pathway to understand and treat advanced breast cancer.
Improving Brain Plasticity
The Shatz Lab at Stanford developed a decoy drug that allowed mice to form new connections as adults, leading to findings that could eventually help people recover from stroke, forms of blindness and Alzheimer's disease.
Parkinson's Diagnosis by Typing on a Keyboard
MIT researchers show how analyzing people's keystrokes as they type can reveal information about the state of their motor function.
Employing CRISPR Technology in Drug Discovery
CRISPR technology will allow AstraZeneca to identify and validate new drug targets in preclinical models that closely resemble human disease.
Cas9: As a Transcriptional Activator
In this technical animation, Wyss Institute researchers instruct how they engineered a Cas9 protein to create a powerful and robust tool for activating gene expression.
Complex 3D DNA structures
MIT biological engineers have created a new computer model that allows them to design the most complex 3D DNA shapes ever produced, including rings, bowls, and geometric structures such as icosahedrons that resemble viral particles.
Top 10 U.S. Biopharma Clusters
Senior news editor Alex Philippidis discusses GEN’s annual ranking of the nation’s most nurturing regions.
Music in Your DNA and a New Species of Human?
Is musical ability genetic? And were there more species of ancient humans than we once thought? SciShow News investigates!
Could Tissue Engineering Mean Personalized Medicine?
Tissue engineer Nina Tandon talks about using pluripotent stem cells to make personalized models of organs on which to test new drugs and treatments, and storing them on computer chips.