GEN UPDATES in biotechnology: Transfection
GEN Technology Updates are composed of articles commissioned for publication by Genetic Engineering & Biotechnology News and of peer-reviewed scientific papers from journals published by Mary Ann Liebert, Inc. They are intended to provide in-depth information and coverage on cutting-edge technologies and trends that are transforming drug discovery and life science research.
In Vitro Nucleic Acid Transfection Methods
Patricia F. Dimond, Ph.D.
Minimizing Off-Target Effects in Transfection
Jay Wang
Distal ERBB2 Promoter Fragment Displays Specific
Transcriptional and Nuclear Binding Activities in ERBB2
Overexpressing Breast Cancer Cells
Laurence Delacroix, Dominique Begon, Guillaume
Chatel, Pascale Jackers, and Rosita Winkle
Development of Luciferase Reporter-Based Cell Assays
Chunfai Lai, Xin Jiang, and Xianqiang Li
Development of a Synthetic Promoter for Macrophage Gene Therapy
Weijing He, Mei Qiang, Wuqiong Ma, Anthony J.
Valente, Marlon P. Quinones, Wen Wang, Robert L.
Reddick, Qifu Xiao, Seema S. Ahuja, Robert A. Clark,
Gregory L. Freeman, and Senlin Li
Interferon-Inducible Mx Gene Expression in Cotton Rats: Cloning, Characterization, and Expression During Influenza Viral Infection
Lioubov M. Pletneva, Otto Haller, David D. Porter, Gregory A. Prince, and Jorge C.G. Blanco

Abr and Bcr, Two Homologous Rac GTPase-Activating Proteins, Control Multiple Cellular Functions of Murine Macrophages
Young Jin Cho, Jess M. Cunnick, Sun-Ju Yi, Vesa Kaartinen, John Groffen, and Nora Heisterkamp
Mol. Cell. Biol., Feb 2007; 27: 899 — 911
Granulogenesis in Non-neuroendocrine COS-7 Cell Induced by EGFP-tagged Chromogranin A Gene Transfection: Identical and Distinct Distribution of CgA and EGFP
Chie Inomoto, Shinobu Umemura, Noboru Egashira, Takeo Minematsu, Susumu Takekoshi, Yoshiko Itoh, Johbu Itoh, Laurent Taupenot, Daniel T. O'Connor, and R. Yoshiyuki Osamura
J. Histochem. Cytochem., Jan 2007; 10.1369/jhc.6A7110.2007
Progesterone Receptors Upregulate Wnt-1 To Induce Epidermal Growth Factor Receptor Transactivation and c-Src-Dependent Sustained Activation of Erk1/2 Mitogen-Activated Protein Kinase in Breast Cancer Cells
Emily J. Faivre and Carol A. Lange
Mol. Cell. Biol., Jan 2007; 27: 466— 480.
Prospective Early Response Imaging Biomarker for Neoadjuvant Breast Cancer Chemotherapy
Kuei C. Lee, Bradford A. Moffat, Anne F. Schott, Rachel Layman, Steven Ellingworth, Rebecca Juliar, Amjad P. Khan, Mark Helvie, Charles R. Meyer, Thomas L. Chenevert, Alnawaz Rehemtulla, and Brian D. Ross
Clin. Cancer Res., Jan 2007; 13: 443—450.
Cases of Mistaken Identity
Chatterjee, R., 2007. Science, Vol. 315, pp 928—931
Comparison of established cell lines at different passages by karyotype and comparative genomic hybridization.
Wenger, S.L. et al. 2004. Bioscience Reports, 24 (6):631—639
Interpretation of cell culture phenomena.
Vierck J.L. et al. 2000. Methods in Cell Science, 22(1): 79—81
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More information on Cutting Edge Transfection Reagents from Roche Applied Science
Protocol for Optimizing Transfection of Adherent Cell Lines
Tips and Tricks on How to Improve Transfection Experiments
Database of cell lines successfully transfected with FuGENE® 6 and HD Transfection Reagents
Additional articles and applications with FuGENE® 6 and HD Transfection Reagents
Passage Number Effects in Cell Lines
Why they happen and what you can do about it
Maintaining High Standards in Cell Culture

