Current Issue

View Larger Image

Past Issues Free Subscriptions
Sponsored
Keywords



Search Results - MAb Production
 More »

  • Membrane Protein Monoclonal Antibodies
    Figure 1 illustrates the relative sizes of a mouse mAb CDR and the extracellular region of ... DNA immunization results in the production of pure target MMP in the membranes of cells ...
    8-1-2013
  • Downstream Process Bottlenecks
    ... cost-effective at large production scale, and are often replaced by reusable equipment." ... Manufacturers of non-mAb proteins still face challenges, Bach says, because the molecular ...
    7-1-2013
  • RuiYi Licenses mAb Development to China's Genor
    labs, an analytical and quality center, and a cGMP clinical production facility. ... especially rheumatoid arthritis. RuiYi Licenses mAb Development to China's Genor
    5-16-2013
  • Heightened Characterization of Therapeutic mAbs Using a Novel...
    Quality control and analysis of monoclonal antibody (mAb) therapeutics is required throughout therapeutic development and production. In particular, deep characterization of ...
    5-15-2013
  • RuiYi, CMC Collaborate to Speed mAb Development
    of protein-based therapeutics for preclinical, clinical trials, and in-market production. ... designed to fight inflammation and cancer RuiYi, CMC Collaborate to Speed mAb Development
    5-14-2013
  • Soligenix, Intrexon Team Up on Dual-Purpose Drug Discovery Initiative
    Soligenix and Intrexon are collaborating to develop and commercialize mAb therapies for ... antibody candidates, followed by production of mAbs targeting melioidosis, while ...
    5-1-2013
  • Separation of Therapeutic Biomolecules
    ... were then refined and converted to a step elution protocol for larger scale production. ... for novel purification methods to isolate mAb fragments that are increasingly being ...
    5-1-2013
  • Boosting Downstream Productivity
    antibody (mAb) market, a subclass of recombinant proteins, was estimated at $40 billion. The development of biopharmaceuticals, from initial lab work through production and ...
    4-15-2013
  • A Cellulose-Based Alkaline-Resistant Affinity Chromatography...
    Protein A chromatography resin is widely used in the production of therapeutic antibodies ... the extremely high potential of KanCapA as the new PA , mAb purification platform.
    3-11-2013
  • Where Downstream Operations Are Headed
    ... It is a production improvement technology, where increasing mAb yield and product quality are the benefits, which may offset the cost of buying additional TFF cassettes." Steve ...
    1-1-2013
  • Inventive Approaches Redefine Downstream Ops
    They now employ the Mab Select SuRe, a high-flow agarose matrix with an alkali-stabilized ... trials, which have necessitated the establishment of large-scale antibody production. Dr. ...
    12-1-2012
  • GE Healthcare Improves Single-Use Abilities
    ... ReadyToRock event. One compared a 100 L mAb process in a single-use format and to the ... of single-use processing for influenza vaccine production in mammalian VERO cell culture. ...
    11-15-2012
  • Lonza to Manufacture OncoMed's Anticancer Antibody Pipeline
    production of OncoMed's cancer stem cell-targeting monoclonal antibody portfolio. This currently includes the early clinical-stage candidates demcizumab (an anti-DLL4 mAb ...
    10-23-2012
  • Antibody Mixture Protects Against Ebola Virus
    the development of a monoclonal antibody (mAb)-based therapy for Ebola virus that ... (RAMP) tobacco plant system, which would allow mass production for a national stockpile. ...
    10-16-2012
  • New Method for "Fingerprinting" Biosimilars
    Unlike generic small molecule drugs, biologic drug production is complex, meaning that ... An Early Predictor of Changes in Higher Order Structure? Figure 3. Comparison of mAb ...
    10-15-2012
  • More »

    Journal Articles

  • Monoclonal Antibodies Against Actinobacillus pleuropneumoniae...
    Jinlin Liu, Jihong Yang, Bin Li, Yanli Liu, Yuting Tu, Jin Zhao, Weicheng Bei, Chao Qi
    Hybridoma
    The rTonB2 was then used as antigen to immunize BALB/c mice for the production of monoclonal antibodies (MAb). Four clones of TonB2-specific MAb secretion hybridomas, 2F2, 2G8, ...
  • Functional Characterization of an IgE-Class Monoclonal Antibody...
    Kelly A.N. Messingham, Amber Onoh, Elizabeth M. Vanderah, George J. Giudice, Janet A. Fairley
    Hybridoma
    from mast cells when triggered with NC16A, and induced keratinocyte production of IL-8. The 395D2 MAb was also able to trigger antigen-specific histamine release from mast ...
  • Optimization of Expression Conditions for Production of Anti...
    Da-Young Park, Jung-Hwan Lee, Yang-Kang So, Young-Kwan Kim, Kinarm Ko, Sang-Won Park, Yong Seok Lee, Yeon Soo Han, Kisung Ko
    Hybridoma
    Optimization of Expression Conditions for Production of Anti-colorectal Cancer Monoclonal ... immunotherapeutic monoclonal antibody (mAb) against colorectal cancer cells in a ...
  • Novel Immunohistochemical Monoclonal Antibody Against Human Glucose...
    Liu Yang, Mingquan Su, Yueyun Ma, Xiaoke Hao
    Hybridoma
    To gain further insight into its possible functions, we generated a novel MAb specific for ... Thus, successful production of GRP78 monoclonal antibodies provides a new powerful tool ...

GEN Webinars

View »

GEN Web Briefs

View »

GEN Poll

More » Poll Results » Archive »

Top Paid Women in Biopharma

Do you think the women on our list of the 20 top paid women executives in biopharma are underpaid?

Suggest a Poll