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Search Results - High-content screening
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  • Toxicity Screens with Increased Insight
    Multiplex High-Content Imaging for Studying Compound Performance Increasing output, ... low volumes, high-throughput screening, and advanced software for collection ...
    10-15-2013
  • PMT-Based Hit Picking for HCA
    and their modulation by diseases, hence the use of the term high content. When HCA applications call for screening chemical libraries in an effort to find compounds that induce ...
    10-1-2013
  • Cell-Based Assays: Getting Back to Basics
    ... are easily isolated and purified. "We have begun formal collaborations with clinicians in which biopsies are performed and cells are isolated and plated for high-content screening. ...
    9-15-2013
  • Novel 3D Cell Culture Systems
    ... The researchers designed the system to be compatible with essentially any automated liquid-handling and high-throughput screening system, as well as high-content screening and ...
    9-15-2013
  • 3D High-Content Analysis of Spheroids
    ... Use of HDPs and the acumen high-content imager improve the preclinical drug screening process and allow for more efficient triaging of the best preclinical candidates. | Principal ...
    9-15-2013
  • Pfizer, Sanford-Burnham Team Up on Obesity, Diabetes Target Research
    Its drug discovery capabilities include ultra-high-throughput screening, high-content screening, phenotypic screening, and target deconvolution technologies. Once the screening ...
    8-13-2013
  • High-Content Imaging Software
    enabling the Orbitor RS plate mover to be used in conjunction with either the ArrayScan XTI high-content analysis reader or the CellInsight NXT high-content screening platform.
    7-1-2013
  • High-Content Screening for Identifying miRNAs Inducing Cardiac...
    High-content screening methods have proven useful in identifying molecules that affect cardiomyocyte differentiation and development, as well as in assessing their toxic effects on ...
    6-25-2013
  • HCS Station
    The scan^R 2.4 high-content screening station is based upon the IX3 inverted microscope frame. The updated screening station can now be incorporated with the fully automated IX83, ...
    6-15-2013
  • Live Content Imaging
    High-content screening (HCS) approaches in microplates-where cells are typically treated, fixed, labeled, and then imaged-have partially alleviated the throughput problem, but ...
    6-1-2013
  • Cenix, Debiopharm Launch Biomarker Collaboration
    project will entail pinpointing potential biomarkers for Debiopharm by using its expertise in combining high-throughput screening with high content assays in cultured human cells. ...
    5-23-2013
  • Seasoned Drugs Offer Therapeutic Gold Mine
    ... Wong's group uses an integrative approach that combines bioinformatics analysis, pathway reconstruction, high-throughput and high-content screening, and chemi-informatics methods ...
    5-15-2013
  • Predicting Drug Toxicity in Humans
    ... "At BRI, we advocate the use of the high-content hepatocyte imaging assay in animal ... Compagnone's team has developed a cell-based high-throughput screening (HTS) methodology ...
    4-1-2013
  • Genome Editing for R&D and Therapeutics
    ... mutations found in Alzheimer's disease. "These cells can be utilized for high-content screening of therapeutic candidates and represent the first isogenic library of cells ...
    3-1-2013
  • High-Content Imaging
    The acumen® hci (high-content imaging) can image and analyze the whole wells of 96- to 1,536-well plates at a resolution of 0.5 µm/pixel. This enables the screening of ...
    3-1-2013
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    Journal Articles

  • High-Content Screening Assay for Activators of the Wnt/Fzd Pathway...
    Kristen M. Borchert, Rachelle J. Sells Galvin, Charles A. Frolik, Laura V. Hale, David L. Halladay, Robin J. Gonyier, O. Joseph Trask, Debra R. Nickischer, Keith A. Houck
    ASSAY and Drug Development Technologies
    High-Content Screening Assay for Activators of the Wnt/Fzd Pathway in Primary Human Cells ASSAY and Drug Development Technologies We have developed a high-content screening (HCS) ...
  • Improving High-Content-Screening Assay Performance by Using Division...
    Chandrasekaran Vasudevan, Natalie Fursov, Patrick Maunder, Mei Cong, Mark Federici, Jeffrey R. Haskins, Thomas Livelli, Zhong Zhong
    ASSAY and Drug Development Technologies
    Improving High-Content-Screening Assay Performance by Using Division-Arrested Cells ASSAY and Drug Development Technologies As cell-based assays are used more commonly in robotic ...
  • High-Content Screening Analysis of the p38 Pathway: Profiling...
    Sandra Ross, Teresa Chen, Violeta Yu, Yanyan Tudor, Dawei Zhang, Longbin Liu, Nuria Tamayo, Celia Dominguez, David Powers
    ASSAY and Drug Development Technologies
    High-Content Screening Analysis of the p38 Pathway: Profiling of Structurally Related p38 α Kinase Inhibitors Using Cell-Based Assays ASSAY and Drug Development Technologies The ...
  • The Use of High-Content Screening for the Discovery and Characterizati...
    Amy Barabasz, Briana Foley, James C. Otto, Anisa Scott, John Rice
    ASSAY and Drug Development Technologies
    The Use of High-Content Screening for the Discovery and Characterization of Compounds That Modulate Mitotic Index and Cell Cycle Progression by Differing Mechanisms of Action ASSAY ...

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