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Search Results - Whole-Genome Analysis
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  • Avoiding "Incidental" Damages
    ... given that it was not necessary to have carried out the analysis in the first place." ... for fully informed consent in clinical whole-genome sequencing, but didn't offer details. ...
    5-15-2013
  • Somatic Mutation Links Port-Wine Birthmarks, SWS, and Melanoma...
    whose affected and unaffected tissue and blood samples underwent whole-genome sequencing. In a separate analysis, researchers detected the mutation in 23 of 26 tissue samples from ...
    5-8-2013
  • Biomarkers Take Center Stage
    ... to develop tests, we improved data-analysis algorithms to reproducibly obtain ... Laser-captured tumor samples will be subjected to low passage whole-genome, exome, and RNA ...
    5-1-2013
  • Comparative Genomics: Insights into Disease Susceptibility
    ... Comparison of the software with other mapping software and variant-calling methods has shown that the MGRC approach to the analysis of whole-genome data is robust, cost-effective, ...
    5-1-2013
  • Ingenuity, Affymetrix Pair Products to Curb Microarray Bottlenecks
    and interpret their study data using Ingenuity Variant Analysis (to identify causal variants from the output of whole-genome and exome sequencing experiments) and iReport (to be ...
    4-8-2013
  • Querying the Cancer Transcriptome
    ... Park. Genomic reads from whole-genome sequencing data containing transposable elements ... Park. This analysis, performed in dozens of cancer samples, allowed identification of many ...
    4-1-2013
  • Computational Bio Problem Solving
    Computational biology involves the analysis, management, and visualization of cellular ... panel of 40-50 genes-let alone a whole genome or whole exome sequence-is still a lot ...
    4-1-2013
  • Advertorial: Axeq Technologies
    ... Axeq shares the expertise of Macrogen in high depth human whole-genome resequencing and analysis capabilities including SNV, CNV, and other structural variations. As a participant ...
    4-1-2013
  • Clinical NGS Takes Step Forward
    for gene panel, exome, and whole-genome data sets. Through the combined offering, Ingenuity will provide content and software for the analysis and biological interpretation of ...
    3-19-2013
  • Gene Expression Analysis Making Inroads
    Advances in genomics technology have made sequence analysis of diverse organisms routine. Scientists armed with whole genome sequence data can now ask questions about genome ...
    3-15-2013
  • Molecular Characterization of CTCs
    ... For molecular analysis, the samples typically are lysed to recover DNA or RNA content from the cells. Amplification (whole genome or targeted pre-amplification) is sometimes ...
    3-15-2013
  • Creative Approaches to Next-Gen Sequencing
    ... set of genes or features in the genome, for example, it may be preferable to enrich for these ahead of time, saving the time, effort, and cost of a whole-genome analysis. ...
    3-1-2013
  • Use of Digital PCR Ramping Up
    PCR (cPCR) and provides scientists the ability to upload their raw qPCR data for analysis. ... extended the use of digital microfluidics to the application of whole-genome haplotyping. ...
    2-15-2013
  • Next-Generation Sequencing in the Clinic
    ... Perhaps the timely analysis of the vast amounts of data from NGS instruments is the ... I am a fan of whole-genome sequencing in cancer research because it gives the whole ...
    2-13-2013
  • Arrivederci, GINA
    The commission's report, Privacy and Progress in Whole Genome Sequencing, stressed that ... to undertake considerable effort and analysis to identify specific individuals." "Even ...
    2-1-2013
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    Journal Articles

  • Altered Gene Expression in Human Adipose Stem Cells Cultured...
    Andrea Hecker, Melanie Grassl, Sven Kinzebach, Hermann Solz, Carsten Sticht, Harald Klüter, Peter Bugert, Karen Bieback, Viet Anh-Thu Ha
    Tissue Engineering, Part A
    A whole genome gene expression analysis was performed and data verified by polymerase chain reaction and protein analyses. Microarray-based screening of 34,039 genes revealed 102 ...
  • Diverse Effects of Cyclic AMP Variants on Osteogenic and Adipogenic...
    Joyce Doorn, Maarten Leusink, Nathalie Groen, Jeroen van de Peppel, Johannes P.T.M. van Leeuwen, Clemens A. van Blitterswijk, Jan de Boer
    Tissue Engineering, Part A
    In addition, a whole-genome expression analysis showed an increase in expression of adipogenic genes in 8-br-cAMP-treated cells. Furthermore, by means of quantitative polymerase ...
  • MicroRNA Expression Profiles in Umbilical Cord Blood Cell Lineages
    Michaela Merkerova, Alzbeta Vasikova, Monika Belickova, Hana Bruchova
    Stem Cells and Development
    Further, we determined mRNA expression profiles using whole-genome microarrays. An ... Comparative analysis revealed 13 miRNAs significantly altered between UCB and BM CD34+ ...
  • Transcriptome Analysis of Organisms with Food Safety Relevance
    Supraja Puttamreddy, Michael D. Carruthers, Melissa L. Madsen, F. Chris Minion
    Foodborne Pathogens and Disease
    1) a short history and description of microarrays and 2) a discussion of studies involving bacterial food safety pathogens that focused on whole genome transcript analysis. ...

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Genome Sequencing and Patient Autonomy

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