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Search Results - Transposons

  • Footprint-Free, Site-Specific Gene Editing
    ... DNA transposons, sometimes called "jumping genes", are naturally occurring mobile DNA ... While most transposons leave behind some mutation when they are excised, the piggyBac ...
    3-1-2013
  • Scientists Effect Biallelic Correction of Alpha1-Antitrypsin...
    An alternative method for removing selection cassettes is to convert them into transposons, and the moth-derived piggyBac DNA transposon is ideally suited to this task, as it can ...
    10-13-2011
  • DNA Cloning Expands into New Horizons
    ... Leitão and colleagues have used a random mutagenesis strategy based on plasposons, which are a class of transposons that facilitate the recovery and identification of interrupted ...
    7-1-2011
  • Spotlight on Opportunities & Innovations
    ... Among the techniques for mutagenesis is mobile DNA technology, using DNA transposons such as piggyBac or Sleeping Beauty to generate insertional mutations. NuPotential is working ...
    7-1-2010
  • Transposagen Wins Over $412K to Develop Rat Model of Colorectal...
    Transposagen claims it currently offers about 95% of the world's existing knockout rat inventory. The firm has pioneered the use of mobile DNA technology including DNA transposons ...
    1-26-2010
  • Silkworm Genome Research Program
    The SGP's website is crawling with genetic resources such as a linkage map and lists of silkworm genes and transposons submitted to public databases. The KAIKO 2D database provides ...
    10-15-2009
  • Next-Gen Presents Array of Opportunities
    ... Recently, we realized we could exploit this method and modify the transposons; we ended up creating an NGS Library." Library preparation currently has three distinct steps: ...
    9-1-2009
  • New Tool Recombineers the DNA of E. coli
    While many systems for genetic engineering in E. coli allow only for modifications at specific positions (e.g., transposons, group II introns), the Red/ET system is sequence ...
    5-15-2009
  • Alu Transposons Identified as Most Abundant Type of Jumping Gene
    ... Laboratories at Emory, the University of Michigan, and the Max Planck Institute for Developmental Biology contributed to the study. Alu Transposons Identified as Most Abundant Type ...
    10-23-2008
  • Identifying MRSA with Multiplex Sequencing
    materials (plasmids and transposons) and hence are transferable across species barriers. ... than the carrier vehicles such as organisms, plasmids, transposons, or genetic cassettes. ...
    3-15-2008
  • JUMPING GENES FOR SAFER GENE DELIVERY
    The advent of new nonviral gene delivery systems using transposons, or "jumping ... She talks about common transposons currently in use and why they would make for safer gene ...
    11-15-2007
  • Safer and More Efficient Gene Delivery Method Suggested
    Molecular biologist and associate biological safety officer Margy Lambert describes the gene-delivery potential of transposons, stretches of DNA capable of jumping from one DNA ...
    9-27-2007
  • Western Honey Bee Genome More Similar to Humans
    ... All organisms' genomes contain common types of transposons, small DNA sequences that move around in a genome that can cause mutations, but there are substantially fewer transposons ...
    10-27-2006
  • Targeted Disruption Using Group II Introns
    Gene knockouts for generating mutant prokaryotes are frequently produced by transposon mutagenesis. Transposons are small DNA segments that have the ability to move from one ...
    7-1-2005
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    Journal Articles

  • Antibiotic Resistance Genes in the Vaginal Microbiota of Primates...
    Robert T. Jeters, Angel J. Rivera, Lisa M. Boucek, Rebecca M. Stumpf, Steve R. Leigh, Abigail A. Salyers
    Microbial Drug Resistance
    Polymerase chain reaction analysis showed that at least some tet(M) and tet(Q) genes were genetically linked to DNA from known conjugative transposons (CTns), Tn916 and CTnDOT. Our ...
  • Distribution of the erm (B) Gene, tet racycline Resistance Genes...
    E. De Leener, A. Martel, A. Decostere, F. Haesebrouck
    Microbial Drug Resistance
    Resistance Genes, and Tn 1545 -like Transposons in Macrolide- and Lincosamide-Resistant ... The presence of transposons of the Tn916/Tn1545 family was also traced in these isolates. ...
  • Transposon Tn 5393 e Carrying the aphA1 -Containing Transposon...
    Amy K. Cain, Ruth M. Hall
    Microbial Drug Resistance
    It is related to several other transposons that carry aphA1b in fragments of differing length, also flanked by copies of IS26. Tn6023 is located in the tnpR gene of Tn5393, which ...
  • Novel Vancomycin-Resistance Transposon, Plasmid Replicon Types...
    Ting-Ting Qu, Qing Yang, Ping Shen, Ze-Qing Wei, Yun-Song Yu
    Microbial Drug Resistance
    CC17 was the main clonal complex in clinical Enterococcus faecium isolates but not in isolates from healthy human subjects. Novel vancomycin-resistance transposons were detected ...

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