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  • Querying the Cancer Transcriptome
    cancer, analyses that evaluate cancer transcriptome information alongside other data will ... of thought-provoking findings, the transcriptome, with its unprecedented and unexpected ...
    4-1-2013
  • Creative Approaches to Next-Gen Sequencing
    ... MYbaits is useful for gaining insights into gene structure, even when only transcriptome ... from western terrestrial garter snake transcriptome sequences were used to enrich genomic ...
    3-1-2013
  • mRNA Sequencing
    The C 1 Single-Cell Auto Prep system now features an mRNA sequencing application that can give researchers an end-to-end workflow for transcriptome analysis of 96 single cells. ...
    3-1-2013
  • Unveiling Biological Complexity with SMRT Sequencing
    ... Koren et al. noted that single molecule sequencing has advantages beyond genome assembly by presenting some preliminary analysis on the corn transcriptome generated by the Joint ...
    2-11-2013
  • The Buzz at ASHG
    ... Fluidigm's C1(tm) Single-Cell Auto Prep System can isolate and examine single cells, grouping them according to unique genomes and transcriptomes, for use in whole transcriptome ...
    1-15-2013
  • Next-Generation Sequencing vs. Microarrays
    ... for gene expression experiments as it provides a more detailed look at the transcriptome. ... Conversely, the various RNA-Seq methods cover all aspects of the transcriptome without any ...
    1-9-2013
  • Systems Biology Tackles Range of Challenges
    A transcriptome analysis showed that as butanol concentration rose, 40 genes were overexpressed, including ones coding for ADH degradation, ABC efflux exporters, the AgmR cluster, ...
    12-1-2012
  • Cerebellar Development Transcriptome Database
    For researchers interested in understanding how the mammalian cerebellum develops, the Cerebellar Development Transcriptome Database (CDT-DB) is a great online resource. The ...
    12-1-2012
  • iPSCs Reveal Somatic Copy Number Mosaicism in Skin Cells
    expression analyses, reverse transcription PCR (RT-PCR), microarrays, complete transcriptome by high-throughput RNA sequencing (RNA-seq), and demethylation of canonical ...
    11-20-2012
  • The Long and the Short of DNA Sequencing
    to greatly improve genome and transcriptome assembly, error rates of ... undulatus , as well as for RNA-Seq reads of the corn ( Zea mays ) transcriptome. ...
    11-16-2012
  • Boosting Gene Expression Profiling
    decreasing the chances of generating a comprehensive analysis of the entire transcriptome. ... alternative splicing events. "Whole transcriptome and exome analysis on both microarrays ...
    11-15-2012
  • Alacris, GSK Make Early-Stage Cancer Research Deal
    Alacris will then suggest which cancer cell lines as well as which cancers are more likely to respond to the inhibitor. This will be based on whole genome and transcriptome data ...
    11-14-2012
  • Visualizing Cell Signaling Pathways
    Cancer Res, 2011. 71(6): p. 2045-55.] Combined experimental and theoretical tools that include biochemical and molecular biology approaches, genome, transcriptome, and proteome ...
    11-1-2012
  • Goldilocks and the Three TFs Make Blood Vessels
    Genome-wide transcriptome analyses further confirmed that rAC-VECs express a complete vascular signature that is similar to adult ECs, including human umbilical vein ECs (HUVECs) ...
    10-19-2012
  • RNA Analysis Unearths Invaluable Insights
    ... However, new gene expression profiling platforms promise to provide better insights into the pathophysiological mechanisms of disease. "We focused on the transcriptome from the ...
    10-15-2012
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    Journal Articles

  • Identification of the Chondrocyte Lineage Using Microfibril-Associated...
    Stephen Rapko, Mindy Zhang, Brenda Richards, Elizabeth Hutto, Sandra Dethlefsen, Stephen Duguay
    Tissue Engineering, Part C: Methods
    Chondrocyte and synovial cell cultures were then examined using a full transcriptome microarray analysis, which revealed cartilage link protein and microfibril-associated ...
  • Sox11 Is Expressed in Early Progenitor Human Multipotent Stromal...
    Benjamin L. Larson, Joni Ylostalo, Ryang H. Lee, Carl Gregory, Darwin J. Prockop
    Tissue Engineering, Part A
    Microarray assays demonstrated progressive changes in the transcriptome of the cells. However, the transcriptomes clustered more closely over time within a single passage, rather ...
  • Determination of the Human Cardiomyocyte mRNA and miRNA Differentiatio...
    Joshua E. Babiarz, Morgane Ravon, Sriram Sridhar, Palanikumar Ravindran, Brad Swanson, Hans Bitter, Thomas Weiser, Eric Chiao, Ulrich Certa, Kyle L. Kolaja
    Stem Cells and Development
    Hierarchical clustering of the mRNA data revealed that the transcriptome of hiPSC cardiomyocytes largely stabilizes 20 days after initiation of differentiation. Nevertheless, ...
  • Hypoxic/Normoxic Preconditioning Increases Endothelial Differentiation...
    Lee-Lee Ong, Wenzhong Li, Jana Kristina Oldigs, Alexander Kaminski, Bernhard Gerstmayer, Christoph Piechaczek, Wolfgang Wagner, Ren-Ke Li, Nan Ma, Gustav Steinhoff
    Tissue Engineering, Part C: Methods
    The transcriptome profile revealed a cluster of 232 downregulated and 498 upregulated genes in cells treated for 24?h under hypoxia. The upregulated genes include angiogenic genes, ...

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