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Search Results - Small Molecules
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  • iRNA's Antiviral Path in Mammals Not Abandoned, Just Less Traveled
    The sequence of these RNA clearly corresponded to the viral genome and they displayed all the characteristics of the main effector molecules of RNAi called the small interfering or ...
    10-11-2013
  • Ovarian Cancer Treatment Options Multiply
    Therefore, despite a small incidence rate (22,240 this year, according to the American ... T-cell immune response against cells with survivin peptides on HLA class I molecules. ...
    10-8-2013
  • A*STAR, Debiopharm Team Up to Develop Epigenetic Cancer Target
    Swiss-based biopharmaceutical company Debiopharm Group signed an exclusive research collaboration to develop oral small molecules targeting a new class of epigenetic modulators. ...
    10-7-2013
  • Workings of Body's Master Energy Regulator Revealed
    nor how binding of these molecules leads to an increase in the activity of the kinase." ... "In contrast, A769662 [a synthetic small molecule regulator] causes profound ...
    10-3-2013
  • Probing Watery Films to Reveal Contours of Membrane Proteins
    Using a small and stable radical with an even higher magnetic property than the hydrogen ... excited nearby water molecules, only when they moved at the same frequency as the dipole. ...
    10-1-2013
  • CROs: Is Yours Meeting Your Needs?
    ... and mortars or some leased space, or small labs for pharmacology and wet lab experiments. ... relative to what we can offer them to help them move their molecules into the clinic." ...
    10-1-2013
  • Tips for Working Optimally with CMOs
    Startups are more likely to devote precious capital to getting their molecules into the ... manufacturing-is a necessity for small to mid-size CMOs, Pekos explains. "Most ...
    10-1-2013
  • One-Step Cloning
    ... were tried, employing different numbers and types of donor molecules of varying sizes. ... Cloning of Repetitive and Very Small Sequences One of the limitations of a few novel ...
    10-1-2013
  • Advertorial: Florida Biologix
    ... vectors, and other biomolecules), purification, aseptic filling (including small molecules, nucleic acids, and proteins), cell therapies, product testing, and regulatory support. ...
    10-1-2013
  • NYC Institutions Launch Drug Development Institute, Partner with...
    The Takeda partnership will focus on developing small chemical molecules, with medicinal chemists and pharmacologists from Takeda set to join investigators from the institutions in ...
    10-1-2013
  • Literature Review: Probing Protein Oligomerization
    ... The ability to regulate AGR2 oligomerization in trans opens the possibility for developing small molecules that regulate its biochemical activity as potential cancer therapeutics. ...
    9-25-2013
  • Fine-Tuning Formulation Processes
    ... For protein drugs those factors are much more important than for small molecules." Since seemingly innocuous formulation changes can pose grave consequences, it is imperative for ...
    9-15-2013
  • Novel 3D Cell Culture Systems
    ... assay or extra/intravasation assay, small-to-medium library screens with a 3D ... and other natural molecules to support the health and viability of the cultured cells. ...
    9-15-2013
  • Progress in Protein Expression Technology
    ... were properly folded and that they bound their small-molecule ligands. More recently, Dr. ... that would not be accessible for whole immunoglobulin G molecules. Research efforts in Dr. ...
    9-15-2013
  • Researchers Chafe as NIH Budgets Shrivel
    there. "The absolute number might seem small, but remember that these are highly ... understand the regulation of important cells and molecules in the cardiovascular system. ...
    9-11-2013
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    Journal Articles

  • Small Molecules Affect Human Dental Pulp Stem Cell Properties...
    Mey Al-Habib, Zongdong Yu, George T.-J. Huang
    Stem Cells and Development
    Small Molecules Affect Human Dental Pulp Stem Cell Properties Via Multiple Signaling Pathways Stem Cells and Development One fundamental issue regarding stem cells for regenerative ...
  • Interaction of Small Molecules with Double-Stranded RNA: Spectroscopic...
    Rangana Sinha, Maidul Hossain, Gopinatha Suresh Kumar
    DNA and Cell Biology
    Interaction of Small Molecules with Double-Stranded RNA: Spectroscopic, Viscometric, and Calorimetric Study of Hoechst and Proflavine Binding to PolyCG Structures DNA and Cell ...
  • Screening for Small Molecules' Bilayer-Modifying Potential Using...
    Helgi I. Ingólfsson, Olaf S. Andersen
    ASSAY and Drug Development Technologies
    ASSAY and Drug Development Technologies Abstract Many drugs and other small molecules used to modulate biological function are amphiphiles that adsorb at the bilayer/solution ...
  • Immunological Detection of Small Organic Molecules in the Presence...
    Catherine S. Rix, Mark R. Sims, David C. Cullen
    Astrobiology
    Immunological Detection of Small Organic Molecules in the Presence of Perchlorates: Relevance to the Life Marker Chip and Life Detection on Mars Astrobiology The proposed ExoMars ...

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