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  • Pharma Touting Phase II/III Wins in Run-Up to ASCO
    Amgen, AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Gilead Sciences, and Roche... with the German CLL Study Group, Roche said that GA101 combined with chlorambucil ...
    5-16-2013
  • FDA Approves Roche EGFR Mutation CDx for NSCLC
    The U.S. Food and Drug Administration (FDA) this week approved Roche Molecular Systems' ... The U.S. Food and Drug Administration this week approved Roche Molecular Systems' cobas® ...
    5-15-2013
  • Biotechs Need to Walk the Walk on Drug Value
    ... Two months later, 10 pharma giants-AbbVie, AstraZeneca (AZ), Boehringer Ingelheim, Bristol-Myers Squibb (BMS), GlaxoSmithKline, Johnson & Johnson, Lilly, Pfizer, Roche, and ...
    5-15-2013
  • Layoffs Imminent at Astellas: Two U.S. Labs to Close
    ... Astellas follows other pharma giants that have shrunk their R&D operations in recent years-a category that includes AstraZeneca, Roche, Pfizer, and Takeda-as companies scramble to ...
    5-14-2013
  • Amgen Forms Joint Venture to Sell Vectibix in China
    in annual sales when the drug was approved by FDA in 2006, Vectibix has faced stiff competition from other mCRC drugs, namely Avastin (bevacizumab), marketed by Roche, and Erbitux. ...
    5-10-2013
  • Companion Diagnostics: 52 Pick-Up
    year) has earlier collaboration agreements with AstraZeneca, Quintiles, and Roche. On the diagnostics side, Roche inked earlier deals with Merck, Clovis Oncology, and Transgene. ...
    5-9-2013
  • Harnessing the Power of Kinase Inhibitors
    ... bicyclic molecules called quinolones, while previously working at Roche. Dr. Gong and her colleagues at Roche were interested in JNK inhibition for a number of disease indications. ...
    5-8-2013
  • BMS Partners Again with Ambrx, in Up-to-$112M-and-Up ADC Collaboration
    Additional terms were not disclosed. Ambrx and BMS are among companies looking to develop ADCs: The list includes Roche (Genentech)'s Kadcyla, approved in February for breast ...
    5-3-2013
  • Separation of Therapeutic Biomolecules
    ... The problem presented by Reinhard Braaz at Roche Diagnostics is the high back pressure during production in a 60 cm diameter packed bed column containing butyl-4-FF, a semi-rigid ...
    5-1-2013
  • The Globalization of IVD Companies
    In 2009, Roche Diagnostics, Siemens Healthcare, Abbott Laboratories, the Ortho Clinical Diagnostics division of Johnson & Johnson, and Beckman Coulter (now Danaher) had 60% of the ...
    5-1-2013
  • Human iPSC-Derived Hepatocytes
    ... Virus uptake is inhibited in a dose dependent fashion by the anti-CD81 blocking antibody. Data are courtesy of Hoffmann-La Roche. Hepatitis viral infections, both HCV and HBV, ...
    5-1-2013
  • Ascletis Obtains Chinese Rights to Janssen HIV Treatment
    clinical-stage hepatitis C protease inhibitor being developed with Roche. Earlier this month, Ascletis and Roche said they would collaborate to develop and commercialize Roche's ...
    4-30-2013
  • Hormone Holds Promise for Replacing Insulin Injections
    Evotec said today that its CureBeta collaboration with Harvard University and Johnson & Johnson's Janssen Pharmaceuticals subsidiary has discovered a new hormone that holds promise ...
    4-26-2013
  • GEN | Biolinks
    ... Revivicor, Inc Rexahn Pharmaceuticals, Inc Rhode Island Economic Development Corporation Rib-X Pharmaceuticals, Inc Richter-Helm Biotec Rigel Pharmaceuticals, Inc Roche Roche ...
  • Layoffs and Breakup at Roche
    Roche today announced the dissolution of its Applied Science Business Area, which is part ... In a statement, Roche said the changes are meant to "streamline decision-making and ...
    4-23-2013
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    Journal Articles

  • A Phellinus baumii Extract Reduces Obesity in High-Fat Diet-Fed...
    Jung-Ran Noh, In-Kyoung Lee, Sun-Yung Ly, Keum-Jin Yang, Gil-Tae Gang, Yong-Hoon Kim, Jung-Hwan Hwang, Bong-Sik Yun, Chul-Ho Lee
    Journal of Medicinal Food
    Male 8-week-old C57BL/6 mice were randomly divided into four groups: control, normal chow diet plus vehicle; HFD-control, high-fat plus vehicle; HFD plus orlistat (Xenical®, Roche...
  • Implementation of a Cost-Effective Unlabeled Probe High-Resolution...
    Annika M. Svensson, Lan-Szu Chou, Cindy Meadows, Christine E. Miller, Robert Palais, Kelli Sumner, Tyler C. Wayman, Rong Mao, Elaine Lyon
    Genetic Testing and Molecular Biomarkers
    platform, the 96-well Roche 480 LightCycler (LC480) instrument. This method replaced the U.S. Food and Drug Administration-approved Roche Factor V Leiden kit assay on the ...
  • Mitochondrial Gene Therapy Augments Mitochondrial Physiology...
    Paula M. Keeney, Caitlin K. Quigley, Lisa D. Dunham, Christina M. Papageorge, Shilpa Iyer, Ravindar R. Thomas, Kathleen M. Schwarz, Patricia A. Trimmer, Shaharyar M. Khan, Francisco R. Portell, Kristen E. Bergquist, James P. Bennett
    Human Gene Therapy and Part B: Methods
    proof-of-principle we tested ProtoFection technology in Parkinson's disease cybrid cells, using mtDNA generated from commercially available human genomic DNA (gDNA; Roche). ...
  • Microarray Analysis and Draft Genomes of Two Escherichia coli...
    Scot E. Dowd, Tawni L. Crippen, Yan Sun, Viktoria Gontcharova, Eun Youn, Arunachalam Muthaiyan, Randall D. Wolcott, Todd R. Callaway, Steven C. Ricke
    Foodborne Pathogens and Disease
    Quantitative reverse transcription-polymerase chain reaction was performed to validate the microarray data. Draft genomes of FRIK966 and FRIK2000 were sequenced using Roche Applied ...

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