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Search Results - Rat Models
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  • Human Disease Models Move Underwater
    ... Ph.D., of the Medical College of Wisconsin, who specializes in gene targeting with rat models of cardiovascular disease but was invited to attend the conference as a guest ...
    10-1-2013
  • First Direct Measurement of Spinal Cord Myelin in MS
    wrote the investigators. "Longitudinal PET studies in LPC and EAE rat models demonstrate that MeDAS uptake changes correlate with associated myelin loss in the spinal cord." ...
    9-24-2013
  • Molecular Imaging Driving Development
    ... pharmacodynamics and pharmacokinetics in preclinical models. Speaking with GEN, Dr. ... a calcium sensor and co-expressed it with a light-sensitive photoreceptor in rat neurons. ...
    8-1-2013
  • Closer-to-Real 3D Cell Culture Advances
    ... hepatotoxicity prediction among different models including the HepG2 (glu/gal) cultured hepatocyte model, primary hepatocytes (rat/Human) HepaRG (tumor derived human hepatocyte) ...
    7-3-2013
  • Live Content Imaging
    The range of exemplified kinetic phenotypic assays includes mono- and co-culture models of ... Figure 2C shows kinetic measurements of neurite outgrowth in 96-well plates from rat ...
    6-1-2013
  • Comparative Genomics: Insights into Disease Susceptibility
    ... manatee, the chinchilla, the naked mole rat, the star-nosed mole, and the white ... mammalian genomes helps in developing models of human disease based on genetic studies ...
    5-1-2013
  • Advances in RNAi Tools and Technologies
    designs to target all human, mouse, and rat genes in highly potent and specific fashion. ... to be highly stable when injected into the bloodstream of animal models, he continues. ...
    4-15-2013
  • Predicting Drug Toxicity in Humans
    ... Biopharmaceutical companies are looking to avoid false positives with their drugs. For instance, troglitazone may be safe in rat models, but 1 in 2,000 humans suffers from fatal ...
    4-1-2013
  • Genome Editing for R&D and Therapeutics
    ... We provide off-the-shelf specific ZFNs to target genes for human, mouse, and rat studies ... has been used to correct a variety of congenital liver diseases in animal models. ...
    3-1-2013
  • Footprint-Free, Site-Specific Gene Editing
    For example, they can be used to create models of disease by changing a wild-type locus to ... Figure 1. Homologous recombination (HR) in rat spermatogonial stem cells (SSCs) only ...
    3-1-2013
  • Taconic to Market Yecuris' Humanized Animal Models
    throughout India through a distribution agreement made earlier this month with Vivo Bio Tech, who gained rights to breed and distribute select Taconic mouse and rat models there. ...
    2-25-2013
  • Crunching Complex Data
    Translating insights gleaned from rodent models into greater knowledge of how humans ... told GEN. "We are talking about rat bronchial epithelial cells versus human ...
    2-15-2013
  • Better, Earlier ADME/Tox Predictions in Cells
    However, we can validate models that answer specific questions. As the use of in vitro ... and Mrp3 (red, baso-lateral) in B-CLEAR® rat hepatocytes. [Qualyst Transport Solutions] ...
    12-1-2012
  • 9 Ways to Optimize Preclinical Imaging
    Absolute T2-weighted and diffusion MRI from rat brain 24 and 48 hours post-tMCAO ... post-uptake, bottom row). Preclinical models and the modalities used within them are ...
    10-22-2012
  • Prizes and Quackery Dominate iPS Cell News
    ... We are putting them into rat and mouse models of disease then we will be in the clinic in 2014 for both programs and hope to enter Phase I later that year. "Our recent insights ...
    10-19-2012
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    Journal Articles

  • Osteoporotic rat models for evaluation of osseointegration of...
    Hamdan S Alghamdi, Jeroen JJP van den Beucken, John Jansen
    Tissue Engineering, Part C: Methods
    Osteoporotic rat models for evaluation of osseointegration of bone implants Tissue Engineering, Part C: Methods Osseointegration of dental and orthopedic bone implants is the ...
  • Immunological Aspects of Rat Models of HTLV Type 1-Infected T...
    Mari Kannagi, Takashi Ohashi, Shino Hanabuchi, Hirotomo Kato, Yoshihiro Koya, Atsuhiko Hasegawa, Takao Masuda, Takashi Yoshiki
    AIDS Research and Human Retroviruses
    Immunological Aspects of Rat Models of HTLV Type 1-Infected T Lymphoproliferative Disease AIDS Research and Human Retroviruses The level of host immune responses against human T ...
  • The Antinociceptive Effect of the Asthma Drug Ibudilast in Rat...
    Aldric T. Hama, Alex Broadhead, Daniel S. Lorrain, Jacqueline Sagen
    Journal of Neurotrauma
    The Antinociceptive Effect of the Asthma Drug Ibudilast in Rat Models of Peripheral and Central Neuropathic Pain Journal of Neurotrauma Abstract Ibudilast, an asthma drug, has ...
  • Tissue-Engineered Thyroid Cell Sheet Rescued Hypothyroidism in...
    Ayumi Arauchi, Tatsuya Shimizu, Masayuki Yamato, Takao Obara, Teruo Okano
    Tissue Engineering, Part A
    Tissue-Engineered Thyroid Cell Sheet Rescued Hypothyroidism in Rat Models After Receiving Total Thyroidectomy Comparing with Nontransplantation Models Tissue Engineering, Part A ...

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