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  • High-Content Screening for Identifying miRNAs Inducing Cardiac...
    High-content screening methods have proven useful in identifying molecules that affect cardiomyocyte differentiation and development, as well as in assessing their toxic effects on ...
    6-25-2013
  • Exploring Exosomal RNA
    Uptake by HeLa cells of exosomes labeled with SYTO® RNASelect(tm) stain: A FLoid® Cell Imaging station was used. Red: Alexa Fluor® 594 phalloidin (allows for visualization of ...
    6-15-2013
  • Cenix, Debiopharm Launch Biomarker Collaboration
    Cenix BioScience will identify predictive biomarkers for Debiopharm Group(tm) preclinical oncology candidates under a collaboration whose value was not disclosed, the companies ...
    5-23-2013
  • Harnessing the Power of Kinase Inhibitors
    The assay development and high-throughput screening system at the European ScreeningPort, Hamburg, Germany. The ~600 kinases that make up the human kinome comprise a group of ...
    5-8-2013
  • Ascletis Obtains Chinese Rights to Janssen HIV Treatment
    Ascletis said today it obtained exclusive rights from Assent R&D Ireland to develop, manufacture, and commercialize the next-generation HIV protease inhibitor (PI) TMC310911 in ...
    4-30-2013
  • Advances in RNAi Tools and Technologies
    RNAi research has capitalized on the ability to design and deliver small interfering RNAs (siRNAs) or short hairpin RNAs (shRNAs) to knock down expression of target genes with ...
    4-15-2013
  • Literature Review: Protein—Now You See It, Now You Don't
    Researchers describe a system for the rapid and complete degradation of proteins in mammalian cells. Figures 1A–B. Auxin-inducible degradation system for controlling protein ...
    3-7-2013
  • Transporter Knockout Cell Lines
    Sigma-Aldrich 3050 Spruce St. UNITED STATES MO 63103 Sigma-Aldrich is a leading Life Science and High Technology company. Our chemical and biochemical products and kits are used in ...
    3-1-2013
  • FLIGHT
    Do you work with Drosophila ? Are you planning any RNAi experiments? If you answered "yes" to those questions, then I have a website that may really help your project take ...
    2-15-2013
  • Alnylam Losses Widened by Tekmira Settlement
    Alnylam Pharmaceuticals finished the fourth quarter and all of 2012 in the red, hurt by a one-time $65 million charge to settle nearly two years of lawsuits vs. Tekmira ...
    2-8-2013
  • Cholesterol Drug Deal Worth Up to $205M
    The Medicines Company will develop and commercialize for Alnylam Pharmaceuticals a series of its RNA interference (RNAi) therapeutics targeting proprotein convertase subtilisin/...
    2-4-2013
  • James Watson Hypothesis Links Cancer to Antioxidants
    In a paper he called "among my most important work since the double helix," James D. Watson. Ph.D., posited a theory that links cancer progression in late stages of the disease to ...
    1-9-2013
  • Costly Cats: Dispelling Allergies-to-Animals Mythology
    The solution likely lies in controlling complex immune reactions rather than creating hypoallergenic pets. If you are even thinking of getting a nonallergenic pet for your allergic ...
    12-12-2012
  • Overcoming Drawbacks of Gene Silencing with RNAi
    Tools for Effective Validation and Utilization Gene silencing by RNA interference has become a key tool in research and drug discovery since its discovery by Andrew Fire and Craig ...
    12-1-2012
  • Screen Reveals Hundreds of Potential HD Targets
    A research team has identified hundreds of potential molecular targets linked to toxicity associated with Huntington's disease (HD), hoping that some of them may lead to new ...
    11-30-2012
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    Journal Articles

  • Directing Neuronal Differentiation of Primary Neural Progenitor...
    Wei Ching Low, Winifred Wing Yiu Yau, Lawrence W. Stanton, Guillaume Marcy, Eyleen Goh, Sing Yian Chew
    DNA and Cell Biology
    Directing Neuronal Differentiation of Primary Neural Progenitor Cells by Gene Knockdown Approach DNA and Cell Biology Directing differentiation of neural stem/progenitor cells ...
  • Insights into Effective RNAi Gained from Large-Scale siRNA Validation...
    Ute Krueger, Tobias Bergauer, Brigitte Kaufmann, Irene Wolter, Sabrina Pilk, Mike Heider-Fabian, Steffi Kirch, Christiane Artz-Oppitz, Meike Isselhorst, Juliane Konrad
    Nucleic Acid Therapeutics
    Insights into Effective RNAi Gained from Large-Scale siRNA Validation Screening Nucleic Acid Therapeutics
  • The Science of Biodefense: RNAi
    Allison Chamberlain, Gigi Kwik Gronvall
    Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science
    The Science of Biodefense: RNAi Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science
  • The Business of RNAi Therapeutics
    Dirk Haussecker
    Human Gene Therapy and Part B: Methods
    The Business of RNAi Therapeutics Human Gene Therapy and Part B: Methods

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