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Search Results - RNAi/siRNA
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  • iRNA's Antiviral Path in Mammals Not Abandoned, Just Less Traveled
    Long doubted, the existence of antiviral RNAi in mammals has finally been confirmed. Two companion studies, published October 11 in Science, have found convincing evidence of ...
    10-11-2013
  • PMT-Based Hit Picking for HCA
    New Tool Reduces Screening Times and Required Data Storage Space Figure 1. Cytation3 optical modules: (A) Orientation of the three optical modules; (B) PMT-based detection using ...
    10-1-2013
  • Transfection Methods Evolving
    Academic research trends continue to drive transfection technology advancements. Researchers hope to use more biologically relevant yet hard-to-transfect cell models in addition to ...
    9-1-2013
  • High-Content Screening for Identifying miRNAs Inducing Cardiac...
    High-content screening methods have proven useful in identifying molecules that affect cardiomyocyte differentiation and development, as well as in assessing their toxic effects on ...
    6-25-2013
  • Exploring Exosomal RNA
    Uptake by HeLa cells of exosomes labeled with SYTO® RNASelect(tm) stain: A FLoid® Cell Imaging station was used. Red: Alexa Fluor® 594 phalloidin (allows for visualization of ...
    6-15-2013
  • Cenix, Debiopharm Launch Biomarker Collaboration
    Cenix BioScience will identify predictive biomarkers for Debiopharm Group(tm) preclinical oncology candidates under a collaboration whose value was not disclosed, the companies ...
    5-23-2013
  • Harnessing the Power of Kinase Inhibitors
    The assay development and high-throughput screening system at the European ScreeningPort, Hamburg, Germany. The ~600 kinases that make up the human kinome comprise a group of ...
    5-8-2013
  • Ascletis Obtains Chinese Rights to Janssen HIV Treatment
    Ascletis said today it obtained exclusive rights from Assent R&D Ireland to develop, manufacture, and commercialize the next-generation HIV protease inhibitor (PI) TMC310911 in ...
    4-30-2013
  • Advances in RNAi Tools and Technologies
    RNAi research has capitalized on the ability to design and deliver small interfering RNAs (siRNAs) or short hairpin RNAs (shRNAs) to knock down expression of target genes with ...
    4-15-2013
  • Literature Review: Protein—Now You See It, Now You Don't
    Researchers describe a system for the rapid and complete degradation of proteins in mammalian cells. Figures 1A–B. Auxin-inducible degradation system for controlling protein ...
    3-7-2013
  • Transporter Knockout Cell Lines
    Sigma-Aldrich 3050 Spruce St. UNITED STATES MO 63103 Sigma-Aldrich is a leading Life Science and High Technology company. Our chemical and biochemical products and kits are used in ...
    3-1-2013
  • FLIGHT
    Do you work with Drosophila ? Are you planning any RNAi experiments? If you answered "yes" to those questions, then I have a website that may really help your project take ...
    2-15-2013
  • Alnylam Losses Widened by Tekmira Settlement
    Alnylam Pharmaceuticals finished the fourth quarter and all of 2012 in the red, hurt by a one-time $65 million charge to settle nearly two years of lawsuits vs. Tekmira ...
    2-8-2013
  • Cholesterol Drug Deal Worth Up to $205M
    The Medicines Company will develop and commercialize for Alnylam Pharmaceuticals a series of its RNA interference (RNAi) therapeutics targeting proprotein convertase subtilisin/...
    2-4-2013
  • James Watson Hypothesis Links Cancer to Antioxidants
    In a paper he called "among my most important work since the double helix," James D. Watson. Ph.D., posited a theory that links cancer progression in late stages of the disease to ...
    1-9-2013
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    Journal Articles

  • RNAi-mediated gene silencing of highly expressed genes in the...
    Howard Brody, Suchindra Maiyuran
    Industrial Biotechnology
    RNAi-mediated gene silencing of highly expressed genes in the industrial fungi Trichoderma reesei and Aspergillus niger Industrial Biotechnology Abstract RNA interference utilizes ...
  • RNAi-Based Knockdown of HBx mRNA in HBx-Transformed and HBV-Producing...
    Young Ha Kim, Joong Hyuk Lee, Nak Whan Paik, Hyune Mo Rho
    DNA and Cell Biology
    RNAi-Based Knockdown of HBx mRNA in HBx-Transformed and HBV-Producing Human Liver Cells DNA and Cell Biology RNA interference (RNAi) is the process of sequence-specific gene ...
  • AAV-Based RNAi Silencing of NADPH Oxidase gp91 phox Attenuates...
    Xiuqing Wang, Lucille Skelley, Bo Wang, Ayesha Mejia, Val Sapozhnikov, Zhongjie Sun
    Human Gene Therapy and Part B: Methods
    AAV-Based RNAi Silencing of NADPH Oxidase gp91 phox Attenuates Cold-Induced Cardiovascular Dysfunction Human Gene Therapy and Part B: Methods Background and Objective. Clinical ...
  • A High-Content RNAi-Screening Assay to Identify Modulators of...
    Shilpi Arora, Christian Beaudry, Kristen M. Bisanz, Chao Sima, Jeffrey A. Kiefer, David O. Azorsa
    ASSAY and Drug Development Technologies
    A High-Content RNAi-Screening Assay to Identify Modulators of Cholesterol Accumulation in Niemann-Pick Type C Cells ASSAY and Drug Development Technologies Abstract Niemann-Pick ...

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