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  • Young Companies in the Money: 25 Firms to Watch
    ... Capital Additional financing participants: RA Capital and undisclosed "blue chip public ... cells of interest Financing leader: RA Capital (new investor) Additional financing ...
    10-2-2013
  • AbbVie, Galapagos Ink Up to $405M CF Collaboration
    The first partnership focuses on developing GLPG0634, a selective JAK1 inhibitor, against rheumatoid arthritis (RA). It was expanded in May to include Crohn's disease. AbbVie ...
    9-24-2013
  • AbbVie, Ablynx Ink Up to $840M RA, SLE Collaboration
    of ALX-0061 in both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). ... indications, led by moderate to severe RA. Humira was last year's top best-selling ...
    9-23-2013
  • How Bad Gums Lead to Arthritis
    The link between gum disease and RA had previously been established but the new study ... In RA patients, the subsequent result is chronic inflammation responsible for bone and ...
    9-13-2013
  • AstraZeneca Drops RA Compound After Phase III Disappointments
    AstraZeneca has decided not to proceed with regulatory filings for its rheumatoid arthritis candidate fostamatinib. AstraZeneca Drops RA Compound After Phase III Disappointments
    6-4-2013
  • GSK Grabs MorphoSys RA Candidate in Deal Worth Up to $548M
    which has concluded Phase I/II development for mild to moderate rheumatoid arthritis (RA). ... moderate rheumatoid arthritis. GSK Grabs MorphoSys RA Candidate in Deal Worth Up to $548M
    6-3-2013
  • AbbVie Expands Galapagos Collaboration to Include Crohn's Disease
    of GLPG0634 beyond rheumatoid arthritis (RA), for which the companies are about to ... will start early next year, and take place at the same time as the Phase IIb RA trial. ...
    5-17-2013
  • Bayer Prostate Cancer Drug Gains FDA Approval
    Bayer HealthCare said yesterday it is weeks away from joining Algeta in bringing to the U.S. market their advanced prostate cancer drug Xofigo® (radium Ra 223 dichloride) ...
    5-16-2013
  • Study: Protein Secreted by Certain Fat Cells Can Trigger RA
    messenger RNA for the RA-associated protein profactor D (pro-FD) in its mouse model study. ... Based on his team's discovery of pro-factor D in mice with RA, Banda and his colleagues ...
    5-8-2013
  • Biomarkers Take Center Stage
    ... including rheumatoid arthritis (RA), Crohn's disease, and psoriasis, among others. ... drugs)-naïve RA (rheumatoid arthritis) vs. knee OA (osteoarthritis) patient cohorts. ...
    5-1-2013
  • Biosimilars: 10 Drugs to Watch
    ... U.S. study recruiting participants as of April 17, according to ClinicalTrials.gov (NCT01682512) Celltrion and Hospira: Conducting Phase I trial in South Korea of CT-P10 for RA and ...
    4-22-2013
  • Biosimilars: Not So Far So Fast
    ... NHL, Merck with MK8808 in RA patients, as well as South Korean Celltrion in a joint venture with Hospira, testing CT-P10 in a Phase I trial for RA and another Phase I for lymphoma. ...
    3-15-2013
  • Receptos Licenses AbbVie Antibody for Co-Development
    ... The AbbVie immunology pipeline also includes two Phase II drug candidates-BT-061 for rheumatoid arthritis (RA) and psoriasis, and GLPG0634, also for RA. AbbVie completed a ...
    3-13-2013
  • Merck Doubles Lycera Bet to $600M+
    psoriasis, and rheumatoid arthritis (RA). "There are substantial unmet medical ... holds only North American rights, and the RA drug, MK-8457. Merck's need to boost its ...
    2-12-2013
  • Top 10 VC & Biopharma Equity Deals of 2012
    Series D financing Participating firms: ARCH Venture Partners, Forbion Capital Partners, RA Capital Management, Third Rock Ventures, TVM Capital, and two undisclosed investors 4 ...
    2-8-2013
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    Journal Articles

  • Monoclonal Antibodies 2H10 and 4E6 Against RA-V from Rubia cordifolia

    Hybridoma
    Monoclonal Antibodies 2H10 and 4E6 Against RA-V from Rubia cordifolia Hybridoma
  • Effect of Retinoic Acid on Leptin, Glycerol, and Glucose Levels...
    Seong-Eui Hong, In-Sook Ahn, Hun-Soon Jung, D. Vernon Rayner, Myoung-Sool Do
    Journal of Medicinal Food
    To elucidate the effects of retinoic acids (RAs) on adipogenesis and insulin sensitivity, we treated mature adipocytes with two different kinds of RA, 9-cis-RA and all-trans-RA. ...
  • Aberrant Reactive Oxygen and Nitrogen Species Generation in Rheumatoid...
    Darren C. Phillips, H.K. Irundika Dias, George D. Kitas, Helen R. Griffiths
    Antioxidants & Redox Signaling
    Aberrant Reactive Oxygen and Nitrogen Species Generation in Rheumatoid Arthritis (RA): Causes and Consequences for Immune Function, Cell Survival, and Therapeutic Intervention ...
  • Association Study of MIA3 rs17465637 Polymorphism with Cardiovascular...
    Mercedes García-Bermúdez, Raquel López-Mejías, Carlos González-Juanatey, Alfonso Corrales, Santos Castañeda, José A. Miranda-Filloy, Carmen Gómez-Vaquero, Benjamín Fernández-Gutiérrez, Alejandro Balsa, Dora Pascual-Salcedo, Ricardo Blanco, Isidoro González-Álvaro, Javier Llorca, Javier Martín, Miguel A. González-Gay, Benjamín Fernández-Gutierrez, Isidoro González-Alvaro
    DNA and Cell Biology
    DNA and Cell Biology Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease ... Because of that, we assessed the MIA3 rs17465637 polymorphism in 1505 RA Spanish patients ...

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