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  • Flow Chemistry: Continuous Synthesis and Purification of Pharmaceutica...
    Cambridge MA UNITED STATES shortprograms.mit.edu/fc
    7-8-2013
  • Improving Proteomics Approaches
    semi-automation, as exemplified by her company's PureSpeed protein purification system. ... Rainin's technologic competitors in ultra-small-scale protein purification are gravity ...
    5-15-2013
  • Productivity Boost for Biopurification
    In most cases, at least two chromatography steps are required to complete the purification... A case study using Amsphere JWT 203 protein A stationary phase for the purification of an ...
    5-15-2013
  • Highlights from AACR
    EMD Millipore launched the Amicon® Pro purification system for protein purification in a single device. The device can be configured for different applications, including ...
    5-15-2013
  • Critical Tools for Oligo Characterization
    BioSpring has entered a commercial manufacturing agreement with Sanofi for therapeutic oligonucleotide manufacturing. LC/MS Reduces Sample Prep In-process analysis of purification ...
    5-1-2013
  • Separation of Therapeutic Biomolecules
    for HIC, RPC, and multimodal chromatographic purification of therapeutic biomolecules. ... large-scale downstream separation and purification protocols often introduce unwanted ...
    5-1-2013
  • Twin Effort Hones In on Membrane Proteins
    We use specific patented reagents to carry out the extraction and purification of ... in the upstream isolation, purification, and crystallization of native membrane proteins. ...
    5-1-2013
  • Blood RNA Sample Prep
    collection, preservation, and purification of RNA from whole blood samples. The system consists of Vacuette® RNAgard blood tubes and the BioMaxi(tm) blood RNA purification kit. ...
    5-1-2013
  • Testing for Residual Host Cell Protein & DNA
    drug product following purification. The FDA requires manufacturers to report how much residual HCP or DNA from the host cell remains in the drug substance after purification. ...
    5-1-2013
  • Goodwin, Coldstream Team Up to Tackle ADCs
    GBI offerings include cell culture and purification process development, scale-up, GLP manufacturing and cGMP manufacturing services for cell culture-derived biopharmaceuticals. ...
    4-25-2013
  • Boosting Downstream Productivity
    (Fabs)," said Hagwall. "In Fab purification, Capto adhere is already established ... removal efficiency in downstream purification linked to a high dynamic binding ...
    4-15-2013
  • Single-Use Bioreactor Roundup
    ... Areas of growth include microbial fermentation, cell therapy, personalized medicine, sensing technologies, and, of course, purification. With this in mind, single-use acceptance is ...
    4-15-2013
  • Hand-Held Homogenization Tool
    to make nucleic acids accessible for purification, amplification, sequencing, or get ... In order to demonstrate the quality of lysate, we performed complete DNA purification ...
    4-15-2013
  • Adjusting pH During Viral Inactivation
    used in monoclonal antibody purification processes to inactivate large enveloped viruses. ... 10 of large enveloped viruses (e.g., X-MuLV) in several commercial purification processes. ...
    4-15-2013
  • Poland Invests in Biotech Infrastructure
    ... Our analytical and purification labs also have the best available systems." Zien adds: "We intend to build a pilot plant that will have two 1,000 liter capacity bioprocessing units ...
    4-15-2013
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    Journal Articles

  • Novel Chimerical Endolysins with Broad Antimicrobial Activity...
    Sofia Fernandes, Daniela Proença, Cátia Cantante, Filipa Antunes Silva, Clara Leandro, Sara Lourenço, Catarina Milheiriço, Hermínia de Lencastre, Patrícia Cavaco-Silva, Madalena Pimentel, Carlos São-José, Herminia de Lencastre, Carlos Sao-Jose
    Microbial Drug Resistance
    However, large-scale production and purification of endolysins is frequently impaired due to their low solubility. In addition, a large number of endolysins appear to exhibit ...
  • Collagen I Scaffolds Cross-Linked with Beta-Glycerol Phosphate...
    Roman J. Krawetz, Jaymi T. Taiani, Yiru Elizabeth Wu, Shiying Liu, Guoliang Meng, John R. Matyas, Derrick E. Rancourt
    Tissue Engineering, Part A
    with an efficiency of >80% without purification and/or lineage-specific cell selection. ... Interestingly, without purification of the differentiated cells from the collagen I ...
  • Six-Transmembrane Epithelial Antigen of the Prostate (STEAP1...
    Rasilaben J. Vaghjiani, Sonia Talma, Christopher L. Murphy
    Tissue Engineering, Part A
    However, lack of cell-specific markers thwarts full realization of this as it prevents their identification in vivo, and subsequent purification. In the present study, to ensure ...
  • Combinatorial Human Progenitor Cell Transplantation Optimizes...
    Gillian I. Bell, Michael T. Meschino, Jennifer M. Hughes-Large, Heather C. Broughton, Anargyros Xenocostas, David A. Hess
    Stem Cells and Development
    Using purification of multiple progenitor subtypes based on a conserved stem cell function, high aldehyde dehydrogenase (ALDH) activity (ALDHhi), we have recently shown that ...

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