Current Issue

View Larger Image

Past Issues Free Subscriptions
Sponsored
Keywords



Search Results - Protein Therapeutics
 More »

  • RuiYi Licenses mAb Development to China's Genor
    with them to deliver novel, breakthrough therapeutics for the Chinese healthcare system." ... includes two monoclonal antibodies that target G protein-coupled receptors (GPCRs). ...
    5-16-2013
  • Heightened Characterization of Therapeutic mAbs Using a Novel...
    digestion variability, and minimizes the generation of method-induced degradation products commonly observed in bottom-up characterization approaches for protein therapeutics. ...
    5-15-2013
  • RuiYi, CMC Collaborate to Speed mAb Development
    CMC Biologics is a CMO that specializes in custom services for scale up, as well as cGMP manufacture of protein-based therapeutics for preclinical, clinical trials, and in-market ...
    5-14-2013
  • Companion Diagnostics: 52 Pick-Up
    ... to measure the associated protein product when an ALK gene rearrangement is present. ... Metamark will also be entitled to royalties on worldwide net sales of therapeutics and any ...
    5-9-2013
  • The Tumor Microenvironment as a Drug Target, Part II
    ... can complicate the challenge of developing therapeutics to target cancer pathophysiology. ... target is FAP (fibroblast activation protein), a cell surface serine protease ...
    5-7-2013
  • Ligand Buys Potential Milestone/Royalty Portfolio in Up To $4...
    assets, and broaden that portfolio beyond small molecule therapeutics into biologics. ... mammalian cell lines for therapeutic protein production, such as monoclonal ...
    4-30-2013
  • Ascletis Obtains Chinese Rights to Janssen HIV Treatment
    which aims to provide innovative therapeutics for important medical needs in China," ... growth factor (VEGF) and kinesin spindle protein (KSP), also known as eglin 5 (Eg5). ...
    4-30-2013
  • Celgene, Forma Team Up to Develop Protein Homeostasis Drug Candidates
    Forma Therapeutics Holdings and Celgene are collaborating in an effort to discover, develop, and commercialize protein homeostasis target-regulating drug candidates. Up-front ...
    4-29-2013
  • GEN | Biolinks
    ... Inc Prosidion, Ltd Protagonist Therapeutics, Inc Protech Technology Enterprise Protein Sciences Corporation Protein Simple ProteoNic BV Proterro, Inc PsychoGenics Inc. ...
  • EpiVax and BioAtla Merge Screening Technologies
    EpiVax focuses on immunogenicity screening for protein therapeutics, immunogenicity mitigation, and T cell-driven vaccine design, using a suite of in silico tools. These tools are ...
    4-24-2013
  • Alzheimer's: Lilly Investment Signals R&D Shift
    therapeutics, told The Wall Street Journal the acquisition was part of a new Lilly approach to fighting Alzheimer's focused on fighting both the accumulation of tau protein that ...
    4-17-2013
  • Exploring GPCRs as Therapeutic Targets
    Recent years have seen an explosion of disease-relevant research on G-protein coupled ... at the "American Society for Pharmacology and Experimental Therapeutics" meeting. ...
    4-15-2013
  • Stockholm-Uppsala Region Ups the Ante
    ... Olink, Vivolux, a drug discovery firm focused on cancer therapeutics, and BioLamina. ... BinaryBio, which provides solutions for protein modeling, protein structure ...
    4-15-2013
  • Advances in RNAi Tools and Technologies
    derepression, respectively, of mRNA or protein levels of the miRNA's targets can confirm ... of siRNAs in RNAi-mediated therapeutics, shRNAs are also important tools for ...
    4-15-2013
  • Single-Use Bioreactor Roundup
    ... This includes manufacturers of such products as protein biologicals, vaccines, and now ... the development of a new generation of therapeutics, the single-use bioreactor will be ...
    4-15-2013
  • More »

    Journal Articles

  • Identification of the Chondrocyte Lineage Using Microfibril-Associated...
    Stephen Rapko, Mindy Zhang, Brenda Richards, Elizabeth Hutto, Sandra Dethlefsen, Stephen Duguay
    Tissue Engineering, Part C: Methods
    Methods for the lineage identification of cell or tissue-engineered therapeutics must ... analysis, which revealed cartilage link protein and microfibril-associated glycoprotein-2 ...
  • Bone Tissue Engineering and Regeneration: From Discovery to the...
    Regis J. O'Keefe, Jeremy Mao
    Tissue Engineering, Part B: Reviews
    biomechanical forces, and gene and protein regulatory factors for sustained function. ... and strategies for translation of fundamental discoveries into clinical therapeutics.
  • Isolation and Identification of Cancer Stem-Like Cells in Esophageal...
    Dingzhi Huang, Quanli Gao, Liping Guo, Chunpeng Zhang, Wei Jiang, Hongxia Li, Jing Wang, Xiaohong Han, Yuankai Shi, Shih Hsin Lu
    Stem Cells and Development
    Western blot showed a higher expression of ß-catenin protein in "Tip"-SP cells. All these ... of tumorigenesis for prevention and enhanced selectivity of antitumor therapeutics.
  • Rapamycin As an Antiaging Therapeutic?: Targeting Mammalian Target...
    Andrew R. Mendelsohn, James W. Larrick
    Rejuvenation Research
    toxic insoluble protein aggregates accumulate. On the basis of these results, modulation of mTORC1 function is a promising target for the development of therapeutics for ...

GEN Webinars

View »

GEN Web Briefs

View »

GEN Poll

More » Poll Results » Archive »

Genome Sequencing and Patient Autonomy

Do you think ACMG’s recent recommendations for reporting incidental clinical sequencing results undermine patient autonomy?

Suggest a Poll