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Search Results - Protein Folding
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  • Imposter Amino Acid Mimics Serine, Kinks Neuroproteins, Prompts...
    etiology of neurodegenerative diseases characterized by protein aggregation and tangles. ... The possibility that environmental factors can trigger abnormal folding in proteins ...
    9-26-2013
  • Removing the Receptor Deconvolution Bottleneck
    10% using techniques such as standard protein chips or immunoprecipitation and mass ... This allows for normal trafficking of the proteins to the cell surface, correct folding in ...
    8-1-2013
  • Nudging Difficult-to-Express Proteins Along
    proper targeting, insertion, folding, and efficient accumulation of integral membrane proteins in the E. coli membrane," Dr. Kim said. The protein candidates for expression ...
    6-15-2013
  • Drug Target Research Center Planned for UMass Amherst
    Nearly 50 researchers will be associated with Models to Medicine. One of them, Lila Gierasch, runs a lab focused on how protein homeostasis networks facilitate proper folding in ...
    6-7-2013
  • Separation of Therapeutic Biomolecules
    ... Dr. Hearn stated that water is fundamental in protein folding, mainly due to its role in defining hydrogen bonding and hydrophobic interactions: "water is indispensable for ...
    5-1-2013
  • Boosting Downstream Productivity
    Downstream processing steps can represent up to 60% of the production costs for a protein, ... such as charge variants, glycosylation-, folding-, and truncated mAb-variants. "As ...
    4-15-2013
  • Scientists Print 3D Materials Resembling Biological Tissues
    The researchers demonstrate that the printed material can make folding movements similar ... The droplets can be printed with protein pores to form pathways through the network that ...
    4-4-2013
  • The Genesis of a Discovery: First Steps
    In the 1940s it was still being debated as whether it was the nuclear protein, the DNA or ... great flexibility to allow folding of the structure to fit into the cell nucleus. ...
    4-1-2013
  • DNA to Hang Your Hat On
    single strands of DNA to direct the folding of a long, single strand of DNA, viral ... biological experiments to model complex protein assemblies. 3D DNA Origami Scientists ...
    3-20-2013
  • Increasing Prep HPLC Column Lifetime
    Aggressive Wash Conditions HPLC is a widely used tool in peptide and protein purification. ... During folding of these compounds, polymerization and scrambling may occur, which can lead ...
    3-1-2013
  • Distributed Computing Meets Drug Discovery
    While it won't be the first distributed computing effort in life-sci-Folding@home, based ... is in bridging the chasm between a protein structure of a target, and having a drug ...
    2-28-2013
  • En Bloc Analysis of Epigenetic Publications
    rather chemical modifications of DNA, folding, and complex formation that render genes ... It is also clear that karyopherin, a protein involved in transnuclear transport, is a ...
    2-1-2013
  • Use of Recombinant Human Proteins
    Such authenticity includes structural aspects such as glycosylation, proteolytic processing for mature protein formation, disulfide bond formation, and folding into the proper ...
    1-15-2013
  • Tackling Transfection Tasks
    ... Kim. "We also introduced an endoproteolytic cleavage site to improve protein folding and cytotoxic T lymphocyte processing." In addition, Inovio has developed an ...
    1-1-2013
  • Twisting and Turning for Better Protein Expression
    ... In those situations DNA2.0's approach can improve secretion and folding. "That's a high-level definition of optimization: not just total protein, but total active protein. Our ...
    1-1-2013
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    Journal Articles

  • Protein Folding and Unfolding Simulations: A New Challenge for...
    Rui M.M. Brito, Werner Dubitzky, J. Rui Rodrigues
    OMICS: A Journal of Integrative Biology
    Protein Folding and Unfolding Simulations: A New Challenge for Data Mining OMICS: A Journal of Integrative Biology One of the unsolved paradigms in molecular biology is the protein ...
  • Inverse Protein Folding in 3D Hexagonal Prism Lattice under HPC...
    Alireza Hadj Khodabakhshi, Ján Manuch, Arash Rafiey, Arvind Gupta
    Journal of Computational Biology
    Inverse Protein Folding in 3D Hexagonal Prism Lattice under HPC Model Journal of Computational Biology Abstract The inverse protein folding problem is that of designing an amino ...
  • Redox-Assisted Protein Folding Systems in Eukaryotic Parasites
    Saikh Jaharul Haque, Tanmay Majumdar, Sailen Barik
    Antioxidants & Redox Signaling
    Redox-Assisted Protein Folding Systems in Eukaryotic Parasites Antioxidants & Redox Signaling Significance: The cysteine (Cys) residues of proteins play two fundamentally important ...
  • Redox-Assisted Protein Folding Systems in Eukaryotic Parasites
    Saikh Jaharul Haque, Tanmay Majumdar, Sailen Barik
    Antioxidants & Redox Signaling
    Redox-Assisted Protein Folding Systems in Eukaryotic Parasites Antioxidants & Redox Signaling Abstract Significance: The cysteine (Cys) residues of proteins play two fundamentally ...

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