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Search Results - Protein Folding
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  • Separation of Therapeutic Biomolecules
    ... Dr. Hearn stated that water is fundamental in protein folding, mainly due to its role in defining hydrogen bonding and hydrophobic interactions: "water is indispensable for ...
    5-1-2013
  • Boosting Downstream Productivity
    Downstream processing steps can represent up to 60% of the production costs for a protein, ... such as charge variants, glycosylation-, folding-, and truncated mAb-variants. "As ...
    4-15-2013
  • Scientists Print 3D Materials Resembling Biological Tissues
    The researchers demonstrate that the printed material can make folding movements similar ... The droplets can be printed with protein pores to form pathways through the network that ...
    4-4-2013
  • The Genesis of a Discovery: First Steps
    In the 1940s it was still being debated as whether it was the nuclear protein, the DNA or ... great flexibility to allow folding of the structure to fit into the cell nucleus. ...
    4-1-2013
  • DNA to Hang Your Hat On
    single strands of DNA to direct the folding of a long, single strand of DNA, viral ... biological experiments to model complex protein assemblies. 3D DNA Origami Scientists ...
    3-20-2013
  • Increasing Prep HPLC Column Lifetime
    Aggressive Wash Conditions HPLC is a widely used tool in peptide and protein purification. ... During folding of these compounds, polymerization and scrambling may occur, which can lead ...
    3-1-2013
  • Distributed Computing Meets Drug Discovery
    While it won't be the first distributed computing effort in life-sci-Folding@home, based ... is in bridging the chasm between a protein structure of a target, and having a drug ...
    2-28-2013
  • En Bloc Analysis of Epigenetic Publications
    rather chemical modifications of DNA, folding, and complex formation that render genes ... It is also clear that karyopherin, a protein involved in transnuclear transport, is a ...
    2-1-2013
  • Use of Recombinant Human Proteins
    Such authenticity includes structural aspects such as glycosylation, proteolytic processing for mature protein formation, disulfide bond formation, and folding into the proper ...
    1-15-2013
  • Tackling Transfection Tasks
    ... Kim. "We also introduced an endoproteolytic cleavage site to improve protein folding and cytotoxic T lymphocyte processing." In addition, Inovio has developed an ...
    1-1-2013
  • Twisting and Turning for Better Protein Expression
    ... In those situations DNA2.0's approach can improve secretion and folding. "That's a high-level definition of optimization: not just total protein, but total active protein. Our ...
    1-1-2013
  • Inventive Approaches Redefine Downstream Ops
    ... same time co-expressing helper elements, folding, and secretion of the Fab, which is now ... Of note are antibody-drug conjugates and modifications of the protein molecule to ...
    12-1-2012
  • Invisible RNAs as Anti-HIV Drug Targets
    Advances in NMR technology have allowed scientists to characterize rare and transient 'excited' protein structures and demonstrate their importance in catalysis, protein folding, ...
    10-9-2012
  • Reinventing Affinity Tags
    ... protein is bound to the resin in the presence of a denaturant (e.g., 8 M urea), the affinity resin can then be incubated with a suitable buffer to allow on-column re-folding ...
    10-1-2012
  • Devising a Protein Formulation Strategy
    monitoring the unfolding and folding kinetics of proteins, varying formulation conditions (e.g., temperature, concentration, pH, buffer), protein-protein interactions, and ...
    9-15-2012
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    Journal Articles

  • Bile Acids, Chaperones, and Mammalian Longevity
    Jens Krøll
    Rejuvenation Research
    Bile acids are also steroid hormones activating specific nuclear receptors and G protein-c... proteins, important for the processes of folding, maintenance, and repair of proteins, ...
  • Identification of Differentially Expressed Proteins in Curcumin...
    Marie-Hélène Teiten, Anthoula Gaigneaux, Sébastien Chateauvieux, Anja M. Billing, Sébastien Planchon, Fred Fack, Jenny Renaut, Fabienne Mack, Claude P. Muller, Mario Dicato, Marc Diederich, Claude Müller
    OMICS: A Journal of Integrative Biology
    Further bioinformatic analysis shows that proteins modulated by curcumin are implicated in protein folding (such as heat-shock protein PPP2R1A; RNA splicing proteins RBM17, DDX39; ...
  • Bacterial Proteome of Streptococcus pneumoniae Through Multidimensiona...
    Xuesong Sun, Hong-Ling Jia, Chuan-Le Xiao, Xing-Feng Yin, Xiao-Yan Yang, Jie Lu, Xiang He, Nan Li, Hui Li, Qing-Yu He, Xue-Song Sun
    OMICS: A Journal of Integrative Biology
    identified proteins are involved in many biological processes including protein biosynthesis, protein folding and proteolysis, cell cycle or regulation and carbohydrate metabolism. ...
  • Unfolded Protein Response after Neurotrauma
    Stephen F. Larner, Ronald L. Hayes, Kevin K.W. Wang
    Journal of Neurotrauma
    Unfolded Protein Response after Neurotrauma Journal of Neurotrauma The endoplasmic reticulum (ER) lumen, which actively monitors the synthesis, folding, and modification of newly ...

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