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Search Results - Protein Expression
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  • RuiYi Licenses mAb Development to China's Genor
    by using the CHEF1® high-productivity expression plasmid of CMC Biologics, in a separate ... includes two monoclonal antibodies that target G protein-coupled receptors (GPCRs). ...
    5-16-2013
  • Improving Proteomics Approaches
    ... than 1,300 structures into its protein database. Susanne Gräslund, Ph.D., discussed various high-throughput methods to generate these proteins within a range of expression hosts. ...
    5-15-2013
  • Mass Spec Provides Peek into PTMs
    ... Glycosylation A frozen human prostate tissue slice (10 µm; distal nontumor) was digested with protein N-glycanaseF to release N-glycans: Expression profiles of two representative ...
    5-15-2013
  • Highlights from AACR
    that its SmartFlare RNA detection probes detect native mRNA or miRNA in live cells in a nontoxic manner without affecting gene expression or production of a protein of interest. ...
    5-15-2013
  • Diversifying Your Antibody Portfolio
    ... and production of anti-host cell protein lysate (HCP) polyclonal antibodies ... manufactured by the pharmaceutical industry in a variety of different expression systems. ...
    5-15-2013
  • RuiYi, CMC Collaborate to Speed mAb Development
    CMC Biologics will use its CHEF1® high-productivity expression plasmid to accelerate ... scale up, as well as cGMP manufacture of protein-based therapeutics for preclinical, ...
    5-14-2013
  • Companion Diagnostics: 52 Pick-Up
    ... for the identification of c-kit protein/CD 117 antigen (c-kit protein) expression in normal and neoplastic formalin-fixed paraffin-embedded tissues for histological evaluation. ...
    5-9-2013
  • Cancer Diagnostics, Pushing the Boundaries
    Molecular techniques and technologies to probe alterations in gene and protein expression that may contribute to the development, progression, prognosis, heterogeneity, therapeutic ...
    5-8-2013
  • The Tumor Microenvironment as a Drug Target, Part II
    ... As their expression profile results predicted, CAFs derived from Her2+ breast cancer ... target is FAP (fibroblast activation protein), a cell surface serine protease ...
    5-7-2013
  • Protein Complex Mutated in about 20% of All Cancers
    the proteins, which are members of a protein complex called BAF (or mammalian SWI/SNF) ... or to allow the expression of genes necessary for the growth or function of the cell. ...
    5-6-2013
  • Two Proteins Found to Block Cancer Metastasis
    ... metastatic-incompetent tumors increased expression of Tsp-1 in the premetastatic lungs. ... activity of prosaposin was contained in only a 5-amino acid peptide region of the protein. ...
    5-1-2013
  • Biomarkers Take Center Stage
    ... Studies published in the past year have looked at somatic mutations, gene copy number aberrations, gene expression abnormalities, protein and miRNA expression, and DNA methylation, ...
    5-1-2013
  • Gene Expression Analysis in Living Cells
    ... include sorting of cells based on gene expression (enabling even higher levels of ... detection of multiple types of biomolecules (such as protein + RNA) in the same sample. ...
    5-1-2013
  • Twin Effort Hones In on Membrane Proteins
    ... sequence or any genetic material from a membrane protein of interest. Synthelis carries out a feasibility study to test the expression conditions and optimize protein activity. ...
    5-1-2013
  • Comparative Genomics: Insights into Disease Susceptibility
    ... Further delving into the functional annotation, protein structure modeling, epigenetics, ... and 59 variants associated with expression levels of a nearby coding gene or ...
    5-1-2013
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    Journal Articles

  • Hepatic Differentiation of Human Embryonic Stem Cells Is Promoted...
    Toshio Miki, Alexander Ring, Jörg Gerlach
    Tissue Engineering, Part C: Methods
    Metabolism, hepatocyte-specific gene expression, protein expression, and hepatic function were evaluated after 20 days. Significantly upregulated hepatic gene expression was ...
  • Consistent Osteoblastic Differentiation of Human Mesenchymal...
    Thomas Cordonnier, Alain Langonné, Jérôme Sohier, Pierre Layrolle, Philippe Rosset, Luc Sensébé, Frédéric Deschaseaux
    Tissue Engineering, Part C: Methods
    Stem Cells with Bone Morphogenetic Protein 4 and Low Serum Tissue Engineering, Part ... the mineral deposition and expression of osteoblastic markers during osteogenesis. ...
  • Identification of the Chondrocyte Lineage Using Microfibril-Associated...
    Stephen Rapko, Mindy Zhang, Brenda Richards, Elizabeth Hutto, Sandra Dethlefsen, Stephen Duguay
    Tissue Engineering, Part C: Methods
    protein and microfibril-associated glycoprotein-2 (MAGP2) as the most differentially expressed transcripts between the culture types. Performance characteristics of gene expression ...
  • Salivary Gland Protein Repertoire from Aedes aegypti Mosquitoes
    Lionel Almeras, Albin Fontaine, Maya Belghazi, Stéphanie Bourdon, Elodie Boucomont-Chapeaublanc, Eve Orlandi-Pradines, Meli Baragatti, Nicole Corre-Catelin, Paul Reiter, Bruno Pradines, Thierry Fusai, Christophe Rogier
    Vector-Borne and Zoonotic Diseases
    Salivary Gland Protein Repertoire from Aedes aegypti Mosquitoes Vector-Borne and Zoonotic ... suggesting that expression of salivary proteins is highly conserved across populations. ...

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