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  • Mass Spec Provides Peek into PTMs
    has relied on the use of chemoenzymatic labeling for the enrichment of protein samples for better detection and analysis. "The detection of O-GlcNAc modifications remains a ...
    5-15-2013
  • Highlights from AACR
    in live cells in a nontoxic manner without affecting gene expression or production of a protein of interest. EMD Millipore also featured its SmartFlare(tm) RNA detection probes. ...
    5-15-2013
  • Diversifying Your Antibody Portfolio
    ... and production of anti-host cell protein lysate (HCP) polyclonal antibodies ... In turn, the developed reagent is ideal for equivalent detection of low and high molecular ...
    5-15-2013
  • Companion Diagnostics: 52 Pick-Up
    ... Diagnostic will apply CST's D5F3 antibody and Ventana's Optiview DAB detection platforms to measure the associated protein product when an ALK gene rearrangement is present. The ...
    5-9-2013
  • Cancer Diagnostics, Pushing the Boundaries
    ... of both DNA and protein markers. The dual cutoffs allow for >90% assay sensitivity and specificity. At AACR, company representatives spoke about the detection of bladder ...
    5-8-2013
  • Biomarkers Take Center Stage
    cancer that will help with cancer detection and personalization of the treatment strategy. ... of a tumor affect how much of a given protein will be in the blood?"-perhaps the tumor ...
    5-1-2013
  • Gene Expression Analysis in Living Cells
    ... of enrichment using additional intracellular markers), live-cell tracking of RNAs, and detection of multiple types of biomolecules (such as protein + RNA) in the same sample. ...
    5-1-2013
  • Comparative Genomics: Insights into Disease Susceptibility
    ... Further delving into the functional annotation, protein structure modeling, epigenetics, ... For genome variant detection, the investigators used Illumina's HiSeq platform to achieve ...
    5-1-2013
  • Testing for Residual Host Cell Protein & DNA
    ... In the case of host-cell proteins, immunological assays (e.g., ELISA) in animals are often used for protein detection. However, given that a broad spectrum of proteins can be ...
    5-1-2013
  • Stockholm-Uppsala Region Ups the Ante
    ... Landegren, an expert in molecular detection and amplification at Uppsala University and a ... BinaryBio, which provides solutions for protein modeling, protein structure ...
    4-15-2013
  • Pfizer, BIND Launch $210M+ Targeted Nanomedicine Collaboration
    system of just being a tiny water droplet, so they avoid immune detection and clearance. ... BIND-014 is designed to selectively target a surface protein upregulated in a broad range ...
    4-2-2013
  • Direct DNA Sequencing Using Nanopore Sensors
    the nanopore and having a high enough spatial resolution to allow single-base detection. ... The most commonly reported biological nanopore is the heptameric protein α-hemolysin, ...
    4-1-2013
  • Epigenetics Opens New Avenues for DNA Research
    ... These changes, which can be used for early detection and in prognostic, risk ... estimated to regulate over 30% of the protein-coding genes, epigenetics develops into a ...
    4-1-2013
  • New Biomarkers Could Offer Vital Clues for Cancer Research
    and vascular disease, that C-reactive protein (CRP) is a biomarker for inflammation and ... the outcome for people with cancer by enhancing detection and treatment approaches. ...
    3-21-2013
  • Meeting the Bioassay Challenge
    temperature storage, oxidation, agitation, different pH, etc. to damage the protein. ... drug, outlier detection methods were used to remove very unusual observations. ...
    3-15-2013
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    Journal Articles

  • Analysis of the Relationship of Leptin, High-Sensitivity C-Reactive...
    Abdul Ridha Abdullah, Haydar A. Hasan, Veena L. Raigangar
    Metabolic Syndrome and Related Disorders
    Analysis of the Relationship of Leptin, High-Sensitivity C-Reactive Protein, Adiponectin, ... could be an important tool for early detection of metabolic syndrome before the ...
  • Molecular Detection and Characterization of Methicillin-Resistant...
    Elena Gómez-Sanz, Myriam Zaragaza, Gilberto Igrejas, Patrícia Poeta, Céline Coelho, Carmen Torres, Hajer Radhouani, Luís Pinto, Carmen Lozano
    Microbial Drug Resistance
    Molecular Detection and Characterization of Methicillin-Resistant Staphylococcus aureus ... typed by molecular methods (S. aureus protein A [spa]-, multilocus sequence typing-, ...
  • Detection of Very High-Level Penicillin-Resistant Variants of...
    M. Catherine McEllistrem, Jennifer M. Adams, Shyam Visweswaran, Saleem A. Khan
    Microbial Drug Resistance
    Detection of Very High-Level Penicillin-Resistant Variants of the Tennessee 23F -4 Clone ... 8 µg/ml) infections in the 7-valent pneumococcal protein conjugate vaccine (PCV7) era. ...
  • Evidence of Increased Oxidative Stress in Aged Mesenteric Lymphatic...
    Sangeetha Thangaswamy, Eric A. Bridenbaugh, Anatoliy A. Gashev
    Lymphatic Research and Biology
    acid reactive substances (TBARS); detection of superoxide and mitochondrial ROS in ... with a reduction in Cu/Zn-SOD protein expression and total SOD enzymatic ...

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Genome Sequencing and Patient Autonomy

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