Current Issue

View Larger Image

Past Issues Free Subscriptions
Sponsored
Keywords



Search Results - Post-Translational Modifications
 More »

  • Unraveling the Transcriptome
    ... resulting from coding single nucleotide polymorphisms and mutations, post-translational modifications, and RNA splicing are represented when referring to cellular proteins. "It ...
    7-1-2013
  • Heightened Characterization of Therapeutic mAbs Using a Novel...
    In particular, deep characterization of glycosylation and other post-translational modifications is required because of their influence on antibody stability, activity, and ...
    5-15-2013
  • Improving Proteomics Approaches
    ... These complexes were for many years believed to be covalent-similar to more common post-translational modifications such as phosphorylation and methylation. Subsequently, the ...
    5-15-2013
  • Mass Spec Provides Peek into PTMs
    Post-translational modifications (PTMs) collectively pertain to a phase in protein biosynthesis that involves changes in a polypeptide chain, resulting in a fully functional ...
    5-15-2013
  • Fluorescence Lifetime Assays
    ... In epigenetics, proteins termed epi-readers (such as the bromodomain-containing family of proteins) are of particular interest, as they recognize post-translational modifications ...
    5-15-2013
  • Glycobiology Analysis Solutions Using HPAE-PAD
    With many biological functions, glycosylation is one of the most important post-translational modifications of eukaryotic cell proteins. Oligosaccharides are covalently attached to ...
    4-18-2013
  • Epigenetics Opens New Avenues for DNA Research
    ... Divalent nickel salts were shown to cause epigenetic changes that include aberrant DNA methylation and post-translational histone modifications, causing changes in chromosomal ...
    4-1-2013
  • The ABCs of Glycoproteins: How to Combine Analytics, Biology...
    This webinar will benefit: Biochemists who identify and characterize biotherapeutic proteins Discovery scientists analyzing post-translational modifications of proteins Development ...
    3-15-2013
  • Plant-Based Protein Biomanufacturing
    Specific kinds of eukaryotic post-translational modifications-such as glycosylation-must also be considered. Target yield is important in designing a protein expression project. ...
    2-15-2013
  • Epigenetics: Promising Field Delivers
    Previously, it was proposed that histone post-translational modifications were the ones responsible for epigenetic inheritance, but to a large extent these models were based on ...
    1-15-2013
  • Eliminating Biological Change after Excision
    Understanding the role of proteins, peptides, and their post-translational modifications in the metabolism of healthy and diseased tissue is crucial to elucidate biological ...
    1-15-2013
  • Cevec Inks Another Cell-Line Licensing Agreement
    These nontumor origin cell lines exhibit high protein expression, have been adapted to serum-free suspension culture, and show post-translational modifications that are human-like, ...
    12-20-2012
  • Epigenetics Reshapes the Therapeutic Arena
    ... modifications that occur on histones," says Bernd Hentsch, Ph.D., CDO at 4SC. Recent years witnessed two major advancements relevant to histone post-translational modifications. ...
    12-1-2012
  • Optimizing Cell Lines Improves Production-Really!
    ... our technology, to material from a stable cell line, and found no detectable differences in intactness, aggregation, charge, or post-translational modifications," he pointed out. ...
    11-15-2012
  • Protein Production Prowess Progresses
    Their efforts can be thwarted by problems ranging from incomplete control over cells' growth conditions to inadequate post-translational modifications. However, progress is being ...
    11-1-2012
  • More »

    Journal Articles

  • The Role of Collagen Crosslinking in Differentiation of Human...
    Hugo Fernandes, Koen Dechering, Eugene Van Someren, Ilse Steeghs, Marion Apotheker, Anouk Leusink, Ruud Bank, Karolina Janeczek, Clemens Van Blitterswijk, Jan de Boer
    Tissue Engineering, Part A
    of the extracellular matrix of bone, and it has structural and instructive properties. Collagen undergoes many post-translational modifications, including extensive crosslinking. ...
  • Redox Proteomics
    D. Allan Butterfield, Isabella Dalle-Donne
    Antioxidants & Redox Signaling
    Proteins are major targets of reactive oxygen and nitrogen species (ROS/RNS) and numerous post-translational, reversible or irreversible modifications have been characterized, ...
  • Cardiovascular Redox and Ox Stress Proteomics
    Vikas Kumar, Timothy Dean Calamaras, Dagmar Haeussler, Wilson Steven Colucci, Richard Alan Cohen, Mark Errol McComb, David Pimentel, Markus Michael Bachschmid
    Antioxidants & Redox Signaling
    Cardiovascular Redox and Ox Stress Proteomics Antioxidants & Redox Signaling Significance: Oxidative post translational protein modifications (OPTMs) have been demonstrated to ...
  • Post-Translational Control of Protein Function by Disulfide Bond...
    Kristina M. Cook, Philip J. Hogg
    Antioxidants & Redox Signaling
    Post-Translational Control of Protein Function by Disulfide Bond Cleavage Antioxidants & ... is largely controlled by the level of expression and by posttranslational modifications. ...

GEN Webinars

View »

GEN Web Briefs

View »

GEN Poll

More » Poll Results » Archive »

Top Paid Women in Biopharma

Do you think the women on our list of the 20 top paid women executives in biopharma are underpaid?

Suggest a Poll