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Search Results - Post-Translational Modifications
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  • Identifying & Isolating High-Producer Clones
    and yeast is their ability to produce complex proteins and, when using human cell lines in particular, to add the correct post-translational modifications to these proteins. ...
    10-15-2013
  • Advertorial: OriGene Technologies
    Proteins with correct post-translational modifications (phosphorylation, glycosylation, etc.) are crucial for biologically relevant structure and functional studies. They are also ...
    10-1-2013
  • Employing Open Access LC/MS In Support of Recombinant Protein...
    Peptide tandem mass spectrometry adds important capabilities including protein identification and site specific analysis of post-translational modifications, and can effectively ...
    9-26-2013
  • 4 Tips for Choosing the Ideal Mass Spec Platform for In-Depth...
    as well as variability due to modifications and mutations of proteins make ... Bottom-up analysis: Protein characterization by comprehensive post-translational ...
    9-6-2013
  • Unraveling the Transcriptome
    ... resulting from coding single nucleotide polymorphisms and mutations, post-translational modifications, and RNA splicing are represented when referring to cellular proteins. "It ...
    7-1-2013
  • Heightened Characterization of Therapeutic mAbs Using a Novel...
    In particular, deep characterization of glycosylation and other post-translational modifications is required because of their influence on antibody stability, activity, and ...
    5-15-2013
  • Improving Proteomics Approaches
    ... These complexes were for many years believed to be covalent-similar to more common post-translational modifications such as phosphorylation and methylation. Subsequently, the ...
    5-15-2013
  • Mass Spec Provides Peek into PTMs
    Post-translational modifications (PTMs) collectively pertain to a phase in protein biosynthesis that involves changes in a polypeptide chain, resulting in a fully functional ...
    5-15-2013
  • Fluorescence Lifetime Assays
    ... In epigenetics, proteins termed epi-readers (such as the bromodomain-containing family of proteins) are of particular interest, as they recognize post-translational modifications ...
    5-15-2013
  • Glycobiology Analysis Solutions Using HPAE-PAD
    With many biological functions, glycosylation is one of the most important post-translational modifications of eukaryotic cell proteins. Oligosaccharides are covalently attached to ...
    4-18-2013
  • Epigenetics Opens New Avenues for DNA Research
    ... Divalent nickel salts were shown to cause epigenetic changes that include aberrant DNA methylation and post-translational histone modifications, causing changes in chromosomal ...
    4-1-2013
  • The ABCs of Glycoproteins: How to Combine Analytics, Biology...
    This webinar will benefit: Biochemists who identify and characterize biotherapeutic proteins Discovery scientists analyzing post-translational modifications of proteins Development ...
    3-15-2013
  • Plant-Based Protein Biomanufacturing
    Specific kinds of eukaryotic post-translational modifications-such as glycosylation-must also be considered. Target yield is important in designing a protein expression project. ...
    2-15-2013
  • Epigenetics: Promising Field Delivers
    Previously, it was proposed that histone post-translational modifications were the ones responsible for epigenetic inheritance, but to a large extent these models were based on ...
    1-15-2013
  • Eliminating Biological Change after Excision
    Understanding the role of proteins, peptides, and their post-translational modifications in the metabolism of healthy and diseased tissue is crucial to elucidate biological ...
    1-15-2013
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    Journal Articles

  • Thioredoxin 1-Mediated Post-Translational Modifications: Reduction...
    Changgong Wu, Andrew M. Parrott, Cexiong Fu, Tong Liu, Stefano M. Marino, Vadim N. Gladyshev, Mohit R. Jain, Ahmet T. Baykal, Qing Li, Shinichi Oka, Junichi Sadoshima, Annie Beuve, William J. Simmons, Hong Li
    Antioxidants & Redox Signaling
    Thioredoxin 1-Mediated Post-Translational Modifications: Reduction, Transnitrosylation, Denitrosylation, and Related Proteomics Methodologies Antioxidants & Redox Signaling ...
  • S -Nitrosylation: Specificity, Occupancy, and Interaction with...
    Alicia M. Evangelista, Mark J. Kohr, Elizabeth Murphy
    Antioxidants & Redox Signaling
    S -Nitrosylation: Specificity, Occupancy, and Interaction with Other Post-Translational Modifications Antioxidants & Redox Signaling Abstract Significance: S-nitrosylation (SNO) ...
  • Does N-Acetylcysteine Modulate Post-Translational Modifications...
    Andrea Henze, Jens Raila, Alexandra Scholze, Walter Zidek, Martin Tepel, Florian J Schweigert
    Antioxidants & Redox Signaling
    Does N-Acetylcysteine Modulate Post-Translational Modifications of Transthyretin in Hemodialysis Patients? Antioxidants & Redox Signaling It is assumed that effects of the thiol ...
  • Redox Regulation of Nuclear Post-Translational Modifications...
    Geoffrey Gloire, Jacques Piette
    Antioxidants & Redox Signaling
    Redox Regulation of Nuclear Post-Translational Modifications During NF-κB Activation Antioxidants & Redox Signaling Abstract The transcription factor NF-?B controls the expression ...

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