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  • Mass Spec Provides Peek into PTMs
    ... in proteins/peptides are tagged with azido sugars by using a mutant galactosyltransferase; 2) with the use of a multifunctional reagent, the tagged peptides are captured via ...
    5-15-2013
  • Advertorial: Agilent Technologies
    ... as little as 10-15 µL, resulting in a concentration factor as high as 24X, accelerating time-to-results by rapidly producing plate after plate of mass spectrometry-ready peptides. ...
    5-15-2013
  • Cash-Strapped Unigene Gets $1M Boost from Nordic
    "The 302 molecule and family of peptides are extremely interesting and have been ... As such, we are confident these peptides will deliver an efficacy and combination of ...
    5-9-2013
  • Algeta Expands Cancer Drug Collaboration with Lumiphore
    metal isotopes [radiotracers] and covalently attach them to therapeutic antibodies, peptides, proteins, or other receptor targeting molecules will benefit targeted delivery to ...
    5-2-2013
  • Critical Tools for Oligo Characterization
    ... Interestingly, therapeutic oligonucleotides, as well as some peptides and radiopharmaceuticals, are excluded from the scope of International Conference on Harmonization of ...
    5-1-2013
  • Biomarkers Take Center Stage
    ... three variable regions into which distinct peptides are inserted. The resulting three-dimensional surface formed by these peptides interacts and binds to proteins and other ...
    5-1-2013
  • Metabolomics Advances Reshape Dx Arena
    ... Stokes. "Moreover, we digest the starting material with trypsin, which helps to expose the binding site and ensures that single peptides are immunoprecipitated rather than whole ...
    5-1-2013
  • Protein Proteolysis Mix
    Enhanced proteolytic activity achieved through use of Trypsin/Lys-C Mix can result in a 20-40% increase in the number of peptides generated. Trypsin/Lys-C mix is also tolerant to ...
    5-1-2013
  • Opko Health Snaps Up Prolor Biotech in $480M Deal
    Louis-for all proteins and peptides with the exception of four endocrine proteins licensed to Merck. "This transaction is consistent with Opko's stated objective of broadening our ...
    4-24-2013
  • Exploring GPCRs as Therapeutic Targets
    ... However, only injectable peptides have been discovered for this receptor so far." Heptares uses a structure-based drug design platform called StaR, which engineers GPCRs to ...
    4-15-2013
  • Peptide Mapping Biocolumns
    These biocolumns are superficially porous and have a 120Å pore size, which works well for the analysis of the peptides produced by enzymatic digest of proteins. The 2.7 µm ...
    4-15-2013
  • Ipsen Enlists PeptiDream in Search for Therapeutic Peptides
    develop and launch therapeutic peptides to treat serious medical conditions in ... for worldwide rights to the therapeutic peptides resulting from the collaboration, Ipsen ...
    4-10-2013
  • Potential Prion Disease Therapy Uncovered
    PrP is a cell surface receptor for Aβ peptides and helps mediate a number of critical deleterious processes in animal models of the disease. The scientists also note that their ...
    4-4-2013
  • Pfizer, BIND Launch $210M+ Targeted Nanomedicine Collaboration
    Therapeutic payloads or active pharmaceutical ingredients such as small molecules, peptides, proteins, and nucleic acids such as siRNA and mRNA. Controlled-release polymers that ...
    4-2-2013
  • Media's Role in Cell Culture Success
    ... notes Quandt of GE. ADC-free media originally contained peptones and hydrolysates of plant origins consisting of undefined amino acids, peptides, and other components. ...
    4-1-2013
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    Journal Articles

  • A Bioengineered Human Skin Tissue for the Treatment of Infected...
    Christina L. Thomas-Virnig, B. Lynn Allen-Hoffmann
    Advances in Wound Care
    Infection is one of the most common obstacles to the healing of these types of wounds. Host defense peptides (HDPs) possessing a broad spectrum of activity against microorganisms ...
  • A Bioinformatics Approach to Identify Natural Autoantibodies...
    Nada Vasiljevic, Nevena Veljkovic, Tatjana Kosec, Xue-Zhong Ma, Sanja Glisic, Jelena Prljic, Ana Djordjevic Vujicic, Ljiljana Markovic, Donald R. Branch
    Viral Immunology
    complementarities of physicochemical patterns, were synthesized and 80 HCV-negative and 50 HCV-positive blood donor sera were tested by ELISA. These peptides reacted similarly (p?
  • Proteins and Their Peptide Motifs in Acellular Apatite Mineralization...
    Johan Benesch, João F. Mano, Rui L. Reis
    Tissue Engineering, Part B: Reviews
    The aim of this review is to highlight how proteins and (poly)peptides themselves impact mineralization in the human body, and how those could be used and have been used for ...
  • Calcium-Dependent Complex Formation Between PBP2 and Lytic Transglycos...
    Ioulia Nikolaidis, Thierry Izoré, Viviana Job, Nicole Thielens, Eefjan Breukink, Andréa Dessen, Thierry Izore, Andrea Dessen
    Microbial Drug Resistance
    Penicillin-binding proteins (PBPs) catalyze the last steps of PG biosynthesis, namely the polymerization of glycan chains and the cross-linking of stem peptides, and can be either ...

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