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  • Pluristem Wins $3.3M Israeli Grant to Advance Pipeline
    Pluristem's pre-clinical animal models had previously shown PLX cells were potentially effective in nerve pain and muscle damage when administered locally, and in inflammatory ...
    8-6-2013
  • Ban Sunburn Pain without Coppertone
    They report that the pain is caused by a molecule in the skin's epidermis. Blocking this molecule, known as TRPV4, protects against sunburn pain, say the researchers, whose work is ...
    8-6-2013
  • Big Need in IBD: Drugs to Slow Progression
    ... of the disease, though not the severe pain sometimes associated with those symptoms, nor the underlying cause of the condition. Rather, pain is often addressed with ...
    8-1-2013
  • Merck, Bionomics Make Potentially $172M Pact to Search for Chronic...
    to discover and develop novel small molecule candidates for the treatment of chronic pain, including neuropathic pain. The initial period of the research program will be two years. ...
    7-31-2013
  • Pfizer Splitting Commercial Operations Three Ways, Inks Supply...
    include products across multiple therapeutic areas-inflammation and immunology, CV/metabolic diseases, neuroscience and pain, rare diseases and women's/men's health-the firm said. ...
    7-29-2013
  • Transition Scores Rights to Develop Lilly Osteoarthritis Pain...
    small molecule transcriptional regulator for the treatment of osteoarthritis (OA) pain. ... OA may provide pain relief to many who do not adequately respond to therapy with NSAIDs. ...
    7-24-2013
  • EU Commits $4.5B Over 10 Years for Drug Research
    new drug-toxicity prediction models; a new severe-asthma definition; the world's largest database of schizophrenia studies; and research into the mechanisms of chronic pain. ...
    7-11-2013
  • Top 15 Job-Cutting Companies of 2013 (So Far)
    The developer of drugs for CNS disorders and pain cited a need to conserve cash following ... of its Opana ER® (oxymorphone HCl) moderate-to-severe pain drug from reaching the market. ...
    7-11-2013
  • Heading, Literally, into the Future
    ... White did the monkey head transplant. "I remember that the head would wake up, the facial expressions looked like terrible pain and confusion and anxiety in the animal," Dr. ...
    7-10-2013
  • Up to $12M Deal Expands Acorda Offerings to Neuropathic Pain
    the company's offerings to neuropathic pain management and could generate up to $12 ... an FDA-approved drug for neuropathic pain associated with postherpetic neuralgia ...
    7-9-2013
  • Evotec Scores $1.9M Boehringer Milestone Payday
    Ingelheim for advancing an undisclosed pain compound into preclinical development. ... Boehringer Inghelheim rewards partner for advancing an undisclosed pain compound into ...
    7-8-2013
  • Mambalgin Peptide
    ion channels play a major role in pain pathways. Mambalgin-1 suppresses activity in central neurons and peripheral nociceptors, thus blocking pain. Its analgesic effect was not ...
    7-1-2013
  • Endo Axing 700; Seeks Buyers for HealthTronics, Early-Stage Platform
    ER® (oxymorphone HCl) moderate-to-severe pain drug from reaching the market, and sent ... (lidocaine topical) for post-shingles pain. "The changes we are announcing today are ...
    6-6-2013
  • GEN Hall of Shame
    ... from sequestration by pointing the finger entirely at the other side of the aisle, declaring on the Senate floor April 24: "The Republicans like the pain. They like the pain." ...
    5-17-2013
  • Companion Diagnostics: 52 Pick-Up
    ... Xenon Pharmaceuticals and Roche (Genentech) Agreement announced January 9, 2012 Strategic alliance designed to discover and develop companion diagnostics and compounds for pain. ...
    5-9-2013
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    Journal Articles

  • Radiolabeling, Stability Studies, and Pharmacokinetic Evaluation...
    Kusum Vats, Tapas Das, Haladhar D. Sarma, Sharmila Banerjee, M.R.A. Pillai
    Cancer Biotherapy and Radiopharmaceuticals
    of radiopharmaceuticals for palliation of bone pain arising due to skeletal metastases. ... for developing radiolabeled bone pain palliation agents using lanthanide radionuclides. ...
  • Incidence of Hydromorphone-Induced Neuroexcitation in Hospice...
    Justin Kullgren, Vy Le, Warren Wheeler
    Journal of Palliative Medicine
    Journal of Palliative Medicine * Background Hydromorphone is a semi-synthetic opioid that is commonly used for pain management in hospice patients. Some practitioners utilize ...
  • Laparoscopic donor nephrectomy with Transvaginal extraction:...
    T.A. Kishore, Abijit Shetty, Tharun balan, Joshy Jose, Mohammed Iqbal, Mammen M John, K Vinodan
    Journal of Endourologyand Part B, Videourology
    loss, warm ischemia time, post operative pain score, pre and post operative sexual ... The mean pain score was significantly less on post op day 3 and day 4. There was also an ...
  • Effects of OPRM1 A118G Polymorphism on Epidural Analgesia with...
    Zheming Song, Boxiang Du, Kai Wang, Xueyin Shi
    Genetic Testing and Molecular Biomarkers
    less fentanyl doses to achieve adequate pain relief compared with those with the AA ... response to epidural labor analgesia and so optimize postoperative pain control.

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