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Search Results - Oligonucleotides
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  • Targeting Therapeutics with Molecular 'Robots'
    results extend the use of molecular automata beyond analysis by transfecting oligonucleotides into cells, thereby permitting new operations on the surfaces of native cells," Dr. ...
    7-26-2013
  • Just How Versatile Is the Polymerase Chain Reaction?
    The field of synthetic biology has recently exploded in part due to the availability of de novo synthesized sequences using oligonucleotides and PCR-based assembly approaches. ...
    7-25-2013
  • RT-PCR: Ready for Prime Time?
    ... Seegene believes two of its technical achievements will transform diagnostics. Dual Priming Oligonucleotides (DPO(tm)) eliminate typical "noise" problems in multiplex PCR. DPO ...
    7-23-2013
  • Bioproduction Approach Could Build Better Oligonucleotides for...
    A new approach to manufacturing short, single-stranded DNA molecules-oligonucleotides-coul... a new method for generating these oligonucleotides using enzymatics production methods. ...
    5-31-2013
  • Making Vaccines from Parts
    A custom software program calculated the sequences of needed oligonucleotides to build the gene sequences. From there, the genes were built enzymatically in cell-free reactions ...
    5-14-2013
  • Critical Tools for Oligo Characterization
    Oligonucleotides were almost nonexistent in major pharmacopoeias at the time. Now that ... LC/MS is not as routine or straightforward for oligonucleotides, whose synthesis creates a ...
    5-1-2013
  • Biosearch Moving into New Digs for GMP Production
    Biosearch Technologies, a company that specializes in the development and manufacture of GMP-grade oligonucleotides, is moving its GMP manufacturing process into a new GMP ...
    4-18-2013
  • Advances in RNAi Tools and Technologies
    miRNA inhibitors are single-stranded oligonucleotides (with heavy chemical modifications) ... Diehl explains that Cellecta uses a synthesized pool of oligonucleotides to make a library ...
    4-15-2013
  • Development and Evolution of PCR
    ... is the use of "aptamers," small oligonucleotides that have been selected in vitro to ... energy transfer between two annealed oligonucleotides, have also been used in real-time ...
    4-1-2013
  • DNA to Hang Your Hat On
    ... The Karolinska team uses a long single-stranded DNA molecule or scaffold, and then mixes the scaffold with about 200 short, single-stranded oligonucleotides, or staples. As all of ...
    3-20-2013
  • Next-Gen Gene Synthesis Opens a World of New Possibilities
    ... DNA? Church: Gen9 is the only company that I know of actually delivering diverse sets of large DNA constructs assembled from oligonucleotides chemically synthesized on chips. ...
    3-4-2013
  • Biosearch Eyes Europe Growth with Two Acquisitions
    The acquisition will enable DNA Technology, a producer of custom-manufactured synthetic oligonucleotides in Nordic countries, to expand production capabilities and product ...
    2-20-2013
  • Targeting Protein-Protein Interactions
    ... The technology uses chemical building blocks linked to bispecific DNA oligonucleotides via cleavable and noncleavable linkers and exploits the self-assembly of the oligonucleotides ...
    2-15-2013
  • Epigenetics: Promising Field Delivers
    ... This strategy, which can be adapted to other experimental settings, involves the synthesis of tens of thousands of tagged oligonucleotides that contain a library of regulatory ...
    1-15-2013
  • The Buzz at ASHG
    The NimbleGen SeqCap EZ Exome + UTR library contains 2.1 million empirically optimized long oligonucleotides in solution, which includes 64 Mb of coding exons and miRNA regions and ...
    1-15-2013
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    Journal Articles

  • Antisense Oligonucleotides for Therapeutic Interventions in Neuromuscu...
    Olivier Danos
    Human Gene Therapy and Part B: Methods
    Antisense Oligonucleotides for Therapeutic Interventions in Neuromuscular Diseases Human Gene Therapy and Part B: Methods
  • Oligonucleotides as Short as 7-Mers Can Be Used for PCR Amplification
    JOHN VINCENT, HUGH GURLING, GEORG MELMER
    DNA and Cell Biology
    Oligonucleotides as Short as 7-Mers Can Be Used for PCR Amplification DNA and Cell Biology
  • Abstracts from the Third Annual NIH Symposium on Therapeutic...
    Yoon S. Cho-Chung, Serge Beaucage, Victor Marquez, Leonard Neckers, Paul F. Torrence
    Nucleic Acid Therapeutics
    Abstracts from the Third Annual NIH Symposium on Therapeutic Oligonucleotides Nucleic Acid Therapeutics
  • Identification of Differentially Expressed Genes in Human Lymphoblasto...
    Ruxian Lin, Yuning Sun, Chunrong Li, Chunhua Xie, Shengqi Wang
    Nucleic Acid Therapeutics
    Identification of Differentially Expressed Genes in Human Lymphoblastoid Cells Exposed to Irradiation and Suppression of Radiation-Induced Apoptosis with Antisense Oligonucleotides ...

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