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Search Results - Oligonucleotides
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  • Deciphering RNA Secondary Structure
    ... Das, "quantify all the reactivities of the nucleotides in each RNA of every condition." MAP-seq continues to evolve rapidly to enhance multiplexing, to probe oligonucleotides ...
    10-15-2013
  • One-Step Cloning
    ... the GenBank formatted sequence of the final assembled constructs, as well as the required oligonucleotides, and the individually modified DNA fragments needed for the assembly. ...
    10-1-2013
  • Striking Solid Tumors: Transporting Treatments Safely and Effectively
    ... Nanoparticles are also of benefit for the selective delivery of oligonucleotides to tumor cells. Moreover, certain types of nanoparticles have showed some interesting capacity to ...
    9-23-2013
  • Purification Filters and Supports
    They are designed to capture, clean up, desalt, and purify peptides, proteins, and oligonucleotides and are available in molded discs, sheets, rolls, or with embedded carbon, C8, ...
    9-1-2013
  • Targeting Therapeutics with Molecular 'Robots'
    results extend the use of molecular automata beyond analysis by transfecting oligonucleotides into cells, thereby permitting new operations on the surfaces of native cells," Dr. ...
    7-26-2013
  • Just How Versatile Is the Polymerase Chain Reaction?
    The field of synthetic biology has recently exploded in part due to the availability of de novo synthesized sequences using oligonucleotides and PCR-based assembly approaches. ...
    7-25-2013
  • RT-PCR: Ready for Prime Time?
    ... Seegene believes two of its technical achievements will transform diagnostics. Dual Priming Oligonucleotides (DPO(tm)) eliminate typical "noise" problems in multiplex PCR. DPO ...
    7-23-2013
  • Bioproduction Approach Could Build Better Oligonucleotides for...
    A new approach to manufacturing short, single-stranded DNA molecules-oligonucleotides-coul... a new method for generating these oligonucleotides using enzymatics production methods. ...
    5-31-2013
  • Making Vaccines from Parts
    A custom software program calculated the sequences of needed oligonucleotides to build the gene sequences. From there, the genes were built enzymatically in cell-free reactions ...
    5-14-2013
  • Critical Tools for Oligo Characterization
    Oligonucleotides were almost nonexistent in major pharmacopoeias at the time. Now that ... LC/MS is not as routine or straightforward for oligonucleotides, whose synthesis creates a ...
    5-1-2013
  • Biosearch Moving into New Digs for GMP Production
    Biosearch Technologies, a company that specializes in the development and manufacture of GMP-grade oligonucleotides, is moving its GMP manufacturing process into a new GMP ...
    4-18-2013
  • Advances in RNAi Tools and Technologies
    miRNA inhibitors are single-stranded oligonucleotides (with heavy chemical modifications) ... Diehl explains that Cellecta uses a synthesized pool of oligonucleotides to make a library ...
    4-15-2013
  • Development and Evolution of PCR
    ... is the use of "aptamers," small oligonucleotides that have been selected in vitro to ... energy transfer between two annealed oligonucleotides, have also been used in real-time ...
    4-1-2013
  • DNA to Hang Your Hat On
    ... The Karolinska team uses a long single-stranded DNA molecule or scaffold, and then mixes the scaffold with about 200 short, single-stranded oligonucleotides, or staples. As all of ...
    3-20-2013
  • Next-Gen Gene Synthesis Opens a World of New Possibilities
    ... DNA? Church: Gen9 is the only company that I know of actually delivering diverse sets of large DNA constructs assembled from oligonucleotides chemically synthesized on chips. ...
    3-4-2013
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    Journal Articles

  • Inhibitory Oligonucleotides Block the Induction of AP-1 Transcription...
    Petar Lenert, Ae-Kyung Yi, Arthur M. Krieg, Laura L. Stunz, Robert F. Ashman
    Nucleic Acid Therapeutics
    Inhibitory Oligonucleotides Block the Induction of AP-1 Transcription Factor by Stimulatory CpG Oligonucleotides in B Cells Nucleic Acid Therapeutics
  • Carboranyl Oligonucleotides: 4. Synthesis and Physicochemical...
    Agnieszka B. Olejniczak, Maria Koziolkiewicz, Zbigniew J. Lesnikowski
    Nucleic Acid Therapeutics
    Carboranyl Oligonucleotides: 4. Synthesis and Physicochemical Studies of Oligonucleotides Containing 2'- O -( o -Carboran-1-yl)Methyl Group Nucleic Acid Therapeutics
  • Antisense Oligonucleotides: Rising Stars in Eliminating RNA Toxicity...
    Zhihua Gao, Thomas Alexander Cooper
    Human Gene Therapy and Part B: Methods
    Antisense Oligonucleotides: Rising Stars in Eliminating RNA Toxicity in Myotonic Dystrophy ... Among these approaches, antisense oligonucleotides (ASOs) have demonstrated high ...
  • Oligonucleotides as Short as 7-Mers Can Be Used for PCR Amplification
    JOHN VINCENT, HUGH GURLING, GEORG MELMER
    DNA and Cell Biology
    Oligonucleotides as Short as 7-Mers Can Be Used for PCR Amplification DNA and Cell Biology

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