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Search Results - Multiplexing
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  • Molecular Imaging Driving Development
    ... By using fluorophores that differ in their emission spectra, it is possible to examine a combination of antibodies. Such multiplexing studies cannot be performed using radioactive ...
    8-1-2013
  • RT-PCR: Ready for Prime Time?
    ... constraints create an internal control so that specific extension only occurs when both arms anneal. "The DPO technology opened doors for literally unlimited multiplexing," Dr. ...
    7-23-2013
  • Harnessing the Clinical Power of Single Cells
    ... analysis of a few cells, but is limited in multiplexing due to fluorescence spillover. Flow cytometry is very useful for multiplexing up to 10-15 proteins, but requires a large ...
    6-21-2013
  • Thermo Fisher, Proteome Sciences in $2.1M Technology Deal
    simultaneously, with improved accuracy. "The combination of the highest sample multiplexing rates from TMT with the industry-leading Thermo Scientific Orbitrap mass ...
    6-12-2013
  • 6 Considerations for Multiplex qPCR Setup
    The experimental design for multiplexing is more complicated than for single-reaction ... Master mixes specifically formulated for multiplexing are available commercially. When a ...
    5-13-2013
  • Cancer Diagnostics, Pushing the Boundaries
    ... It allowed for multiplexing of up to eight samples on a 316 chip with an average read depth of 2,750 and improved coverage uniformity. Repeat testing confirmed 100% reproducibility ...
    5-8-2013
  • Democratizing Flow Cytometry
    ... to the power of the new technology platforms, providing the capacity for increased multiplexing and permitting identification of dimly staining populations that were previously ...
    3-15-2013
  • Molecular Characterization of CTCs
    ... technologies that increase sensitivity and the level of multiplexing that can be achieved. ... is sometimes beneficial depending on the assay format and level of multiplexing desired. ...
    3-15-2013
  • How to Improve Your Multiplexing Studies
    Multiplexing can be a useful tool for high-throughput imaging and screening. Find out how ... The tips below aim to help initial set-up of multiplexing assays for high-throughput ...
    2-21-2013
  • Use of Digital PCR Ramping Up
    ... the need for titrations and allows for robust multiplexing," explained Dr. Link. Dr. ... processing and sample preparation, multiplexing, and in-line or parallel sample detection. ...
    2-15-2013
  • Improving In Vivo Small Animal Imaging
    Dr. De Lille describes two major trends driving the in vivo imaging industry: multiplexing, or the use of two or more probes or reporters in one animal; and a move away from ...
    2-1-2013
  • Focusing on Multi-Analyte Detection & Analysis
    using only a tiny amount of sample, multiplexing is positioning itself as a premier ... One of the challenges facing multiplexing is the sheer amount of data generated. "We have ...
    12-1-2012
  • Multiplexed Drug Assessment in 3D
    ... From the perspective of signal detection, the combination of luminescent and fluorescent signals in a multiplexing approach is preferable to a fluorescence-only multiplexing ...
    12-1-2012
  • Multiplexing Takes Research from Bench to Bedside
    Find out how Bio-Rad's Bio-Plex ® suspension array system has contributed to research findings in Dr. Francis Spinale and Dr. Steven Kornlau's laboratories and may impact the ...
    11-28-2012
  • Improving HCA with Laser Scanning Imaging
    ... Serial PMTs enable simultaneous four-color fluorescence detection for multiplexing studies enabling high-content information to be calculated for every object. High-content data ...
    11-15-2012
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    Journal Articles

  • SNaPshot Assay in Quantitative Detection of Allelic Nondisjunction...
    Debarati Ghosh, Sailesh Gochhait, Disha Banerjee, Anindita Chatterjee, Swagata Sinha, Krishnadas Nandagopal
    Genetic Testing and Molecular Biomarkers
    Conclusions: The SNaPshotTM assay is quantitative and permits multiplexing for detection of allelic non-disjunction. Inclusion of additional informative chromosome 21-specific ...
  • Multiplexed Staining of Live Human Embryonic Stem Cells for Flow...
    Andrew B.J. Prowse, John Wilson, Geoffrey W. Osborne, Peter P. Gray, Ernst J. Wolvetang
    Stem Cells and Development
    Our multiplexing approach allows for the addition of internal controls and reduces sample-to-sample variation, while offering a significant reduction in time and reagent ...
  • SNaPshot Assay in Quantitative Detection of Allelic Nondisjunction...
    Debarati Ghosh, Sailesh Gochhait, Disha Banerjee, Anindita Chatterjee, Swagata Sinha, Krishnadas Nandagopal
    Genetic Testing and Molecular Biomarkers
    Conclusions: The SNaPshot assay is quantitative and permits multiplexing for detection of allelic nondisjunction. Inclusion of additional informative chromosome 21-specific markers ...
  • Optimizing PCR Assays for DNA-Based Cancer Diagnostics
    Qing Lu, Dennis Carson, Benjamin J. Raphael, Yu-Tsueng Liu, Vineet Bafna, Ali Bashir
    Journal of Computational Biology
    a novel alternating multiplexing strategy that makes efficient detection possible. ... Additionally, we prove that the suggested multiplexing strategy is optimal in breakpoint ...

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