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  • Growing and Preparing Adult Stem Cells
    ... In his post-doctoral research, Dr. Hanna had employed mathematical models to show that a ... Efficiency approached 100% from mouse and human cells, and the time needed to produce the ...
    10-15-2013
  • Thwarting Greatwall May Trigger Mitotic Collapse and Suppress...
    To date, most Greatwall studies have used Drosophila models. But now a murine model has ... Essential to the researchers' work was the use of a conditional knockout of the mouse ...
    10-9-2013
  • Hypertension Drug May Aid Cancer Treatment
    how an angiotensin inhibitor improved the delivery of chemotherapy drugs and oxygen throughout tumors by increasing blood flow in mouse models of breast and pancreatic cancer. ...
    10-2-2013
  • Human Disease Models Move Underwater
    ... Aneuploidy-or an abnormal number of chromosomes-is universally observed in all types of human cancer, yet genetic mouse models of these diseases rarely feature aneuploidy. This ...
    10-1-2013
  • Snag-Free Induction of Pluripotency in Adult Cells
    In his postdoctoral research, Dr. Hanna had employed mathematical models to show that a ... Efficiency approached 100% from mouse and human cells, and the time needed to produce the ...
    9-18-2013
  • Novel 3D Cell Culture Systems
    ... highlighting "the need to use in vitro models more representative of native tissue when ... protein and stromal mouse fibroblasts NIH3T3 expressing a red fluorescent protein. ...
    9-15-2013
  • BGI Subsidiary Joins San Antonio 1000 Cancer Genome Project
    A total 1,200 patients have agreed to have their tumor tissues sampled and transplanted to mouse models, with the goal of targeting genetic mutations for drug selection and ...
    9-12-2013
  • Bacteria from Lean Humans Can Slim Obese Mice
    ... These findings suggest that more complex interactions between diet, body mass, and gut microbiota underlie human metabolic disturbances than previously understood. The mouse models ...
    9-5-2013
  • Taconic to Promote and Sell Medicyte Hepatocyte Products
    The Taconic tADMET portfolio is a collection of genetically and tissue humanized mouse models, as well as in vitro tools and services that aim to improve the predictability of drug ...
    9-4-2013
  • Transfection Methods Evolving
    ... cells allows extrapolating findings from such animal models. Nucleofection(tm) of neurons in 24-well culture plates: Mouse cortical neurons were transfected after 6 DIV with ...
    9-1-2013
  • CRISPR/Cas Comes of Age-Almost
    The scientists built multiple sequence alignments and hidden Markov models for 45 Cas ... short RNAs to induce precise cleavage at endogenous genomic loci in human and mouse cells. ...
    9-1-2013
  • Copper Appears to Play Key Role in Alzheimer's
    ... The scientists observed this phenomenon in both mouse and human brain cells. The researchers then looked at the impact of copper exposure on mouse models of Alzheimer's disease. In ...
    8-20-2013
  • New Animal Models for Two Prion Diseases
    Massachusetts Medical School, have developed novel mouse models for two fatal human prion protein (PrP) diseases, fatal familial insomnia (FFI) and Creutzfeldt-Jakob disease (CJD). ...
    8-19-2013
  • Myelin Repair Foundation, Gencia Partner to Speed Up MS Drug...
    The DTA model displays characteristics reminiscent of the progressive form of MS, not yet available in other mouse models. Investigators will assess the myelin regenerating ...
    8-14-2013
  • Human MCP Cells Make Decellularized Murine Heart Beat Again
    scaffold could have for transplantation, drug testing models, and understanding heart development. For the project, the research team first decellularized a mouse heart. ...
    8-13-2013
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    Journal Articles

  • Lessons from Mouse Models of Thyroid Cancer
    Caroline S. Kim, Xuguang Zhu
    Thyroid
    Lessons from Mouse Models of Thyroid Cancer Thyroid Background: Thyroid cancer is the most common endocrine tumor and is increasing in incidence. The aim of this study was to ...
  • Analysis: Mouse Models of Glucose Sensor Biocompatibility
    Karl E. Friedl
    Diabetes Technology & Therapeutics
    Analysis: Mouse Models of Glucose Sensor Biocompatibility Diabetes Technology & Therapeutics
  • Effects of Telfairia occidentalis (Fluted Pumpkin; Cucurbitaceae...
    Abidemi J. Akindele, Mutiu Y. Ajao, Flora R. Aigbe, Uchenna S. Enumah
    Journal of Medicinal Food
    Effects of Telfairia occidentalis (Fluted Pumpkin; Cucurbitaceae) in Mouse Models of Convulsion, Muscle Relaxation, and Depression Journal of Medicinal Food Telfairia occidentalis ...
  • Pharmacokinetics and Dosimetry of 111 In/ 188 Re-Labeled PEGylated...
    Yi-Yu Lin, Chih-Hsien Chang, Jia-Je Li, Michael G. Stabin, Ya-Jen Chang, Liang-Cheng Chen, Ming-Hsien Lin, Yun-Long Tseng, Wuu-Jyh Lin, Te-Wei Lee, Gann Ting, Cheng Allen Chang, Fu-Du Chen, Hsin-Ell Wang
    Cancer Biotherapy and Radiopharmaceuticals
    Pharmacokinetics and Dosimetry of 111 In/ 188 Re-Labeled PEGylated Liposomal Drugs in Two Colon Carcinoma-Bearing Mouse Models Cancer Biotherapy and Radiopharmaceuticals Abstract ...

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